5zsw
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==RBM10-RRM2 domain and its lung cancer related mutant== | |
| - | + | <StructureSection load='5zsw' size='340' side='right'caption='[[5zsw]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5zsw]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZSW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZSW FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zsw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zsw OCA], [http://pdbe.org/5zsw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zsw RCSB], [http://www.ebi.ac.uk/pdbsum/5zsw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zsw ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Disease == | ||
| + | [[http://www.uniprot.org/uniprot/RBM10_HUMAN RBM10_HUMAN]] TARP syndrome. TARP syndrome (TARPS) [MIM:[http://omim.org/entry/311900 311900]]: A disorder characterized by the Robin sequence (micrognathia, glossoptosis and cleft palate), talipes equinovarus and cardiac defects. Note=The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:20451169</ref> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/RBM10_HUMAN RBM10_HUMAN]] May be involved in post-transcriptional processing, most probably in mRNA splicing. Binds to RNA homopolymers, with a preference for poly(G) and poly(U) and little for poly(A) (By similarity).<ref>PMID:18315527</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Qin, H]] | ||
| + | [[Category: Classical folding and binding mode]] | ||
| + | [[Category: Rna binding protein]] | ||
Revision as of 06:41, 23 May 2019
RBM10-RRM2 domain and its lung cancer related mutant
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