5xz6

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==Crystal Structure of Phosphofructokinase from Staphylococcus aureus in complex with adenylylimidodiphosphate, the ATP analogue==
==Crystal Structure of Phosphofructokinase from Staphylococcus aureus in complex with adenylylimidodiphosphate, the ATP analogue==
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<StructureSection load='5xz6' size='340' side='right' caption='[[5xz6]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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<StructureSection load='5xz6' size='340' side='right'caption='[[5xz6]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5xz6]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XZ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XZ6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5xz6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_st228 Staphylococcus aureus subsp. aureus st228]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XZ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XZ6 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pfkA, SAOUHSC_01807 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1074919 Staphylococcus aureus subsp. aureus ST228])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/6-phosphofructokinase 6-phosphofructokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.11 2.7.1.11] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/6-phosphofructokinase 6-phosphofructokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.11 2.7.1.11] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xz6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xz6 OCA], [http://pdbe.org/5xz6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xz6 RCSB], [http://www.ebi.ac.uk/pdbsum/5xz6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xz6 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xz6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xz6 OCA], [http://pdbe.org/5xz6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xz6 RCSB], [http://www.ebi.ac.uk/pdbsum/5xz6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xz6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/A0A0D1I869_STAAU A0A0D1I869_STAAU]] Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.[HAMAP-Rule:MF_00339][SAAS:SAAS01078966]
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[[http://www.uniprot.org/uniprot/PFKA_STAA8 PFKA_STAA8]] Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.[HAMAP-Rule:MF_00339]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: 6-phosphofructokinase]]
[[Category: 6-phosphofructokinase]]
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[[Category: Large Structures]]
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[[Category: Staphylococcus aureus subsp. aureus st228]]
[[Category: Tian, T]]
[[Category: Tian, T]]
[[Category: Wang, C L]]
[[Category: Wang, C L]]

Revision as of 07:23, 23 May 2019

Crystal Structure of Phosphofructokinase from Staphylococcus aureus in complex with adenylylimidodiphosphate, the ATP analogue

PDB ID 5xz6

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