4wh6
From Proteopedia
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==Crystal structure of HCV NS3/4A protease variant R155K in complex with Asunaprevir== | ==Crystal structure of HCV NS3/4A protease variant R155K in complex with Asunaprevir== | ||
| - | <StructureSection load='4wh6' size='340' side='right' caption='[[4wh6]], [[Resolution|resolution]] 1.99Å' scene=''> | + | <StructureSection load='4wh6' size='340' side='right'caption='[[4wh6]], [[Resolution|resolution]] 1.99Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4wh6]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WH6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WH6 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4wh6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1a Hepatitis c virus subtype 1a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WH6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WH6 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2R9:N-(TERT-BUTOXYCARBONYL)-3-METHYL-L-VALYL-(4R)-4-[(7-CHLORO-4-METHOXYISOQUINOLIN-1-YL)OXY]-N-{(1R,2S)-1-[(CYCLOPROPYLSULFONYL)CARBAMOYL]-2-ETHENYLCYCLOPROPYL}-L-PROLINAMIDE'>2R9</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2R9:N-(TERT-BUTOXYCARBONYL)-3-METHYL-L-VALYL-(4R)-4-[(7-CHLORO-4-METHOXYISOQUINOLIN-1-YL)OXY]-N-{(1R,2S)-1-[(CYCLOPROPYLSULFONYL)CARBAMOYL]-2-ETHENYLCYCLOPROPYL}-L-PROLINAMIDE'>2R9</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wf8|4wf8]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wf8|4wf8]]</td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wh6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wh6 OCA], [http://pdbe.org/4wh6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wh6 RCSB], [http://www.ebi.ac.uk/pdbsum/4wh6 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wh6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wh6 OCA], [http://pdbe.org/4wh6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wh6 RCSB], [http://www.ebi.ac.uk/pdbsum/4wh6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wh6 ProSAT]</span></td></tr> |
</table> | </table> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Hepatitis c virus subtype 1a]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Ali, A]] | [[Category: Ali, A]] | ||
[[Category: Schiffer, C A]] | [[Category: Schiffer, C A]] | ||
Revision as of 08:43, 23 May 2019
Crystal structure of HCV NS3/4A protease variant R155K in complex with Asunaprevir
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