4v4o

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==Crystal Structure of the Chaperonin Complex Cpn60/Cpn10/(ADP)7 from Thermus Thermophilus==
==Crystal Structure of the Chaperonin Complex Cpn60/Cpn10/(ADP)7 from Thermus Thermophilus==
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<StructureSection load='4v4o' size='340' side='right' caption='[[4v4o]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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<StructureSection load='4v4o' size='340' side='right'caption='[[4v4o]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4v4o]] is a 42 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. This structure supersedes and combines the now removed PDB entries [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1we3 1we3] and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1wf4 1wf4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V4O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4V4O FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4v4o]] is a 42 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. This structure supersedes the now removed PDB entries [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1we3 1we3] and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1wf4 1wf4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V4O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4V4O FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4v4o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v4o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4v4o RCSB], [http://www.ebi.ac.uk/pdbsum/4v4o PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4v4o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v4o OCA], [http://pdbe.org/4v4o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4v4o RCSB], [http://www.ebi.ac.uk/pdbsum/4v4o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4v4o ProSAT]</span></td></tr>
</table>
</table>
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{{Large structure}}
 
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CH60_THET2 CH60_THET2]] Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity).[HAMAP-Rule:MF_00600] [[http://www.uniprot.org/uniprot/CH10_THET2 CH10_THET2]] Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity).
[[http://www.uniprot.org/uniprot/CH60_THET2 CH60_THET2]] Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity).[HAMAP-Rule:MF_00600] [[http://www.uniprot.org/uniprot/CH10_THET2 CH10_THET2]] Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity).
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4v4o" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Chaperonin|Chaperonin]]
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*[[Chaperonin 3D structures|Chaperonin 3D structures]]
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*[[Heat Shock Proteins|Heat Shock Proteins]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
[[Category: Iwata, S]]
[[Category: Iwata, S]]
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[[Category: Folding]]
[[Category: Folding]]
[[Category: Groel]]
[[Category: Groel]]
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[[Category: Roe]]
 
[[Category: Hsp10]]
[[Category: Hsp10]]
[[Category: Hsp60]]
[[Category: Hsp60]]
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[[Category: Roe]]

Revision as of 09:02, 23 May 2019

Crystal Structure of the Chaperonin Complex Cpn60/Cpn10/(ADP)7 from Thermus Thermophilus

PDB ID 4v4o

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