4v4o
From Proteopedia
(Difference between revisions)
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==Crystal Structure of the Chaperonin Complex Cpn60/Cpn10/(ADP)7 from Thermus Thermophilus== | ==Crystal Structure of the Chaperonin Complex Cpn60/Cpn10/(ADP)7 from Thermus Thermophilus== | ||
- | <StructureSection load='4v4o' size='340' side='right' caption='[[4v4o]], [[Resolution|resolution]] 2.80Å' scene=''> | + | <StructureSection load='4v4o' size='340' side='right'caption='[[4v4o]], [[Resolution|resolution]] 2.80Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[4v4o]] is a 42 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. This structure supersedes | + | <table><tr><td colspan='2'>[[4v4o]] is a 42 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. This structure supersedes the now removed PDB entries [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1we3 1we3] and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1wf4 1wf4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V4O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4V4O FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4v4o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v4o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4v4o RCSB], [http://www.ebi.ac.uk/pdbsum/4v4o PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4v4o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v4o OCA], [http://pdbe.org/4v4o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4v4o RCSB], [http://www.ebi.ac.uk/pdbsum/4v4o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4v4o ProSAT]</span></td></tr> |
</table> | </table> | ||
- | {{Large structure}} | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/CH60_THET2 CH60_THET2]] Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity).[HAMAP-Rule:MF_00600] [[http://www.uniprot.org/uniprot/CH10_THET2 CH10_THET2]] Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity). | [[http://www.uniprot.org/uniprot/CH60_THET2 CH60_THET2]] Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity).[HAMAP-Rule:MF_00600] [[http://www.uniprot.org/uniprot/CH10_THET2 CH10_THET2]] Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity). | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
+ | <div class="pdbe-citations 4v4o" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
- | *[[Chaperonin|Chaperonin]] | + | *[[Chaperonin 3D structures|Chaperonin 3D structures]] |
+ | *[[Heat Shock Proteins|Heat Shock Proteins]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
[[Category: Thermus thermophilus]] | [[Category: Thermus thermophilus]] | ||
[[Category: Iwata, S]] | [[Category: Iwata, S]] | ||
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[[Category: Folding]] | [[Category: Folding]] | ||
[[Category: Groel]] | [[Category: Groel]] | ||
- | [[Category: Roe]] | ||
[[Category: Hsp10]] | [[Category: Hsp10]] | ||
[[Category: Hsp60]] | [[Category: Hsp60]] | ||
+ | [[Category: Roe]] |
Revision as of 09:02, 23 May 2019
Crystal Structure of the Chaperonin Complex Cpn60/Cpn10/(ADP)7 from Thermus Thermophilus
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Categories: Large Structures | Thermus thermophilus | Iwata, S | Koike-Takeshita, A | Masui, R | Murai, N | Shimamura, T | Taguchi, H | Yokoyama, K | Yoshida, M | Adp | Atp | Chaperone | Chaperonin | Cpn10 | Cpn60 | Folding | Groel | Hsp10 | Hsp60 | Roe