4uvd

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==Discovery of pyrimidine isoxazoles InhA in complex with compound 6==
==Discovery of pyrimidine isoxazoles InhA in complex with compound 6==
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<StructureSection load='4uvd' size='340' side='right' caption='[[4uvd]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
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<StructureSection load='4uvd' size='340' side='right'caption='[[4uvd]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4uvd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UVD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UVD FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4uvd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UVD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UVD FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HRW:2-[(4,6-DIMETHYLPYRIMIDIN-2-YL)SULFANYL]-N-[(2Z)-5-[3-(TRIFLUOROMETHYL)BENZYL]-1,3-THIAZOL-2(3H)-YLIDENE]ACETAMIDE'>HRW</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HRW:2-[(4,6-DIMETHYLPYRIMIDIN-2-YL)SULFANYL]-N-[(2Z)-5-[3-(TRIFLUOROMETHYL)BENZYL]-1,3-THIAZOL-2(3H)-YLIDENE]ACETAMIDE'>HRW</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4uve|4uve]], [[4uvg|4uvg]], [[4uvh|4uvh]], [[4uvi|4uvi]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4uve|4uve]], [[4uvg|4uvg]], [[4uvh|4uvh]], [[4uvi|4uvi]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uvd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uvd OCA], [http://pdbe.org/4uvd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4uvd RCSB], [http://www.ebi.ac.uk/pdbsum/4uvd PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uvd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uvd OCA], [http://pdbe.org/4uvd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4uvd RCSB], [http://www.ebi.ac.uk/pdbsum/4uvd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4uvd ProSAT]</span></td></tr>
</table>
</table>
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==See Also==
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*[[Enoyl-Acyl-Carrier Protein Reductase|Enoyl-Acyl-Carrier Protein Reductase]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
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[[Category: Myctu]]
[[Category: Cowan, S]]
[[Category: Cowan, S]]
[[Category: Ghorpade, S]]
[[Category: Ghorpade, S]]

Revision as of 09:07, 23 May 2019

Discovery of pyrimidine isoxazoles InhA in complex with compound 6

PDB ID 4uvd

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