4xe9

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==Crystal structure of the NanB sialidase from Streptococcus pneumoniae in complex with Optactin==
==Crystal structure of the NanB sialidase from Streptococcus pneumoniae in complex with Optactin==
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<StructureSection load='4xe9' size='340' side='right' caption='[[4xe9]], [[Resolution|resolution]] 1.84&Aring;' scene=''>
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<StructureSection load='4xe9' size='340' side='right'caption='[[4xe9]], [[Resolution|resolution]] 1.84&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4xe9]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XE9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XE9 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4xe9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Strpn Strpn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XE9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XE9 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=OPX:(1S,3R,4S)-1-[(CYCLOHEXYLAMINO)METHYL]-3,4-DIHYDROXYCYCLOPENTANESULFONIC+ACID'>OPX</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=OPX:(1S,3R,4S)-1-[(CYCLOHEXYLAMINO)METHYL]-3,4-DIHYDROXYCYCLOPENTANESULFONIC+ACID'>OPX</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">nanB, SP_1687 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=170187 STRPN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xe9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xe9 OCA], [http://pdbe.org/4xe9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xe9 RCSB], [http://www.ebi.ac.uk/pdbsum/4xe9 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xe9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xe9 OCA], [http://pdbe.org/4xe9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xe9 RCSB], [http://www.ebi.ac.uk/pdbsum/4xe9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4xe9 ProSAT]</span></td></tr>
</table>
</table>
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==See Also==
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*[[Sialidase|Sialidase]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Exo-alpha-sialidase]]
[[Category: Exo-alpha-sialidase]]
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[[Category: Large Structures]]
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[[Category: Strpn]]
[[Category: Brear, P]]
[[Category: Brear, P]]
[[Category: Allosteric inhibitor]]
[[Category: Allosteric inhibitor]]

Revision as of 07:09, 29 May 2019

Crystal structure of the NanB sialidase from Streptococcus pneumoniae in complex with Optactin

PDB ID 4xe9

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