Dedicator of cytokinesis protein
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<scene name='75/752233/Cv/8'>Human dedicator of cytokinesis protein 9 DHR-2 domain (DOCK9) complex with Cdc42 and GDP</scene> (PDB code [[2wmn]]). <scene name='75/752233/Cv/9'>GDP interacts with Cdc42</scene>. Water molecules shown as red spheres. <scene name='75/752233/Cv/10'>DOCK9 has extensive contacts with Cdc42</scene><ref>PMID:19745154</ref>. | <scene name='75/752233/Cv/8'>Human dedicator of cytokinesis protein 9 DHR-2 domain (DOCK9) complex with Cdc42 and GDP</scene> (PDB code [[2wmn]]). <scene name='75/752233/Cv/9'>GDP interacts with Cdc42</scene>. Water molecules shown as red spheres. <scene name='75/752233/Cv/10'>DOCK9 has extensive contacts with Cdc42</scene><ref>PMID:19745154</ref>. | ||
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| + | ==3D structures of dedicator of cytokinesis protein== | ||
| + | [[Dedicator of cytokinesis protein 3D structures]] | ||
</StructureSection> | </StructureSection> | ||
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**[[3b13]], [[2yin]] – DOCK2 DHR-2 domain + Rac1 <br /> | **[[3b13]], [[2yin]] – DOCK2 DHR-2 domain + Rac1 <br /> | ||
**[[3a98]] – hDOCK2 N-terminal domain + ELMO1<br /> | **[[3a98]] – hDOCK2 N-terminal domain + ELMO1<br /> | ||
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| + | *Dedicator of cytokinesis protein 7 | ||
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| + | **[[6aj4]] – hDOCK7 DHR-2 domain + Cdc42<br /> | ||
| + | **[[6ajl]] – hDOCK7 DHR-2 domain (mutant) + Cdc42<br /> | ||
*Dedicator of cytokinesis protein 8 | *Dedicator of cytokinesis protein 8 | ||
Revision as of 09:47, 4 June 2019
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3D structures of dedicator of cytokinesis protein
Updated on 04-June-2019
References
- ↑ Su HC. Dedicator of cytokinesis 8 (DOCK8) deficiency. Curr Opin Allergy Clin Immunol. 2010 Dec;10(6):515-20. doi:, 10.1097/ACI.0b013e32833fd718. PMID:20864884 doi:http://dx.doi.org/10.1097/ACI.0b013e32833fd718
- ↑ Yang J, Zhang Z, Roe SM, Marshall CJ, Barford D. Activation of Rho GTPases by DOCK exchange factors is mediated by a nucleotide sensor. Science. 2009 Sep 11;325(5946):1398-402. PMID:19745154 doi:325/5946/1398
