Dedicator of cytokinesis protein

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</StructureSection>
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==3D structures of dedicator of cytokinesis protein==
 
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 
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{{#tree:id=OrganizedByTopic|openlevels=0|
 
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*Dedicator of cytokinesis protein 1
 
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**[[2m0y]] – mDOCK1 SH3 domain – mouse - NMR<br />
 
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**[[3l4c]] – hDOCK1 DHR-1 domain - human<br />
 
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*Dedicator of cytokinesis protein 2
 
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**[[3b13]], [[2yin]] – DOCK2 DHR-2 domain + Rac1 <br />
 
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**[[3a98]] – hDOCK2 N-terminal domain + ELMO1<br />
 
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*Dedicator of cytokinesis protein 7
 
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**[[6aj4]] – hDOCK7 DHR-2 domain + Cdc42<br />
 
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**[[6ajl]] – hDOCK7 DHR-2 domain (mutant) + Cdc42<br />
 
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*Dedicator of cytokinesis protein 8
 
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**[[3vhl]] – mDOCK8 DHR-2 domain + Cdc42<br />
 
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*Dedicator of cytokinesis protein 9
 
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**[[2wm9]] – hDOCK9 DHR-2 domain + Cdc42<br />
 
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**[[1wg7]] – hDOCK9 PH domain - NMR<br />
 
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**[[2wmn]] – hDOCK9 DHR-2 domain + Cdc42 + GDP<br />
 
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**[[2wmo]] – hDOCK9 DHR-2 domain + Cdc42 + GTP<br />
 
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}}
 
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 09:49, 4 June 2019

Human dedicator of cytokinesis protein 9 dimer DHR-2 domain (grey and aqua) complex with Cdc42 (green and olive) and GDP (PDB code 2wmn)

Drag the structure with the mouse to rotate

References

  1. Su HC. Dedicator of cytokinesis 8 (DOCK8) deficiency. Curr Opin Allergy Clin Immunol. 2010 Dec;10(6):515-20. doi:, 10.1097/ACI.0b013e32833fd718. PMID:20864884 doi:http://dx.doi.org/10.1097/ACI.0b013e32833fd718
  2. Yang J, Zhang Z, Roe SM, Marshall CJ, Barford D. Activation of Rho GTPases by DOCK exchange factors is mediated by a nucleotide sensor. Science. 2009 Sep 11;325(5946):1398-402. PMID:19745154 doi:325/5946/1398

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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