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6q3t
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6q3t]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43587 Atcc 43587]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Q3T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6Q3T FirstGlance]. <br> | <table><tr><td colspan='2'>[[6q3t]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43587 Atcc 43587]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Q3T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6Q3T FirstGlance]. <br> | ||
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6q3t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6q3t OCA], [http://pdbe.org/6q3t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6q3t RCSB], [http://www.ebi.ac.uk/pdbsum/6q3t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6q3t ProSAT]</span></td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PH1704 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 ATCC 43587])</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6q3t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6q3t OCA], [http://pdbe.org/6q3t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6q3t RCSB], [http://www.ebi.ac.uk/pdbsum/6q3t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6q3t ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DEGLY_PYRHO DEGLY_PYRHO]] Deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins and reactive carbonyl groups of glyoxals. Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively. Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals. Acts on early glycation intermediates (hemithioacetals and aminocarbinols), preventing the formation of advanced glycation endproducts (AGE) that cause irreversible damage (By similarity). Also displays proteolytic activity (PubMed:11114201).[UniProtKB:Q51732]<ref>PMID:11114201</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 23:12, 5 June 2019
Structure of Protease1 from Pyrococcus horikoshii at room temperature in ChipX microfluidic device
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Categories: Atcc 43587 | Large Structures | Engilberge, S | Girard, E | Olieric, V | Sauter, C | Wijn, R de | Chipx | Counterdiffusion | Crystallophore | Hydrolase | Nucleation | Room temperature | Xo4
