Structural highlights
5bkc is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | , , , |
| Related: | 5bkb, 5bkd, 5bk9, 5bke |
| Activity: | (R)-dichlorprop dioxygenase (2-oxoglutarate), with EC number 1.14.11.44 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
[RDPA_DELAC] Involved in the degradation of the phenoxypropionate herbicides. Catalyzes the enantiospecific cleavage of the ether bond in the herbicid R-dichlorprop ((R)-2-(2,4-dichlorophenoxy)propionate)(R-2,4-DP) and R-mecoprop ((R)-2-(4-chloro-2-methylphenoxy)propionate)(R-2,4-MCPP). It can also accept (RS)-2-(2,4,5-trichlorophenoxy)propionate, (RS)-2-(4-chlorophenoxy)propionate, (RS)-2-(m-chlorophenoxy)propionate, however it can only accept 2-oxoglutarate as oxygen acceptor.[1] [2]
References
- ↑ Westendorf A, Benndorf D, Muller RH, Babel W. The two enantiospecific dichlorprop/alpha-ketoglutarate-dioxygenases from Delftia acidovorans MC1--protein and sequence data of RdpA and SdpA. Microbiol Res. 2002;157(4):317-22. PMID:12501996
- ↑ Westendorf A, Benndorf D, Muller RH, Babel W. The two enantiospecific dichlorprop/alpha-ketoglutarate-dioxygenases from Delftia acidovorans MC1--protein and sequence data of RdpA and SdpA. Microbiol Res. 2002;157(4):317-22. PMID:12501996
