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6f0h
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure ASF1-ip4== | |
| - | + | <StructureSection load='6f0h' size='340' side='right'caption='[[6f0h]], [[Resolution|resolution]] 1.98Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6f0h]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6F0H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6F0H FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6f0f|6f0f]], [[6f0g|6f0g]]</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6f0h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6f0h OCA], [http://pdbe.org/6f0h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6f0h RCSB], [http://www.ebi.ac.uk/pdbsum/6f0h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6f0h ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ASF1A_HUMAN ASF1A_HUMAN]] Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.<ref>PMID:10759893</ref> <ref>PMID:11897662</ref> <ref>PMID:12842904</ref> <ref>PMID:14718166</ref> <ref>PMID:15621527</ref> <ref>PMID:16151251</ref> <ref>PMID:15664198</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Andreani, J]] | ||
| + | [[Category: Bakail, M]] | ||
| + | [[Category: Du, M H.Le]] | ||
| + | [[Category: Guerois, R]] | ||
| + | [[Category: Ochsenbein, F]] | ||
| + | [[Category: Richet, N]] | ||
| + | [[Category: Chaperone]] | ||
| + | [[Category: Protein-peptide complexe]] | ||
Revision as of 05:31, 12 June 2019
Crystal structure ASF1-ip4
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