6k1z
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of farnesylated hGBP1== | |
| - | + | <StructureSection load='6k1z' size='340' side='right'caption='[[6k1z]], [[Resolution|resolution]] 2.31Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6k1z]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6K1Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6K1Z FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAR:FARNESYL'>FAR</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6k1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6k1z OCA], [http://pdbe.org/6k1z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6k1z RCSB], [http://www.ebi.ac.uk/pdbsum/6k1z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6k1z ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GBP1_HUMAN GBP1_HUMAN]] Hydrolyzes GTP to GMP in two consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes.<ref>PMID:22106366</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Du, S]] | [[Category: Du, S]] | ||
| - | [[Category: Xiao, J | + | [[Category: Xiao, J Y]] |
| + | [[Category: Gbp farnesylation]] | ||
| + | [[Category: Hydrolase]] | ||
Revision as of 05:37, 12 June 2019
Crystal structure of farnesylated hGBP1
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