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6o07
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure and mechanism of acetylation by the N-terminal dual enzyme NatA/Naa50 complex== | |
| - | + | <StructureSection load='6o07' size='340' side='right'caption='[[6o07]], [[Resolution|resolution]] 2.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6o07]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6O07 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6O07 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IHP:INOSITOL+HEXAKISPHOSPHATE'>IHP</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-terminal_methionine_N(alpha)-acetyltransferase_NatE N-terminal methionine N(alpha)-acetyltransferase NatE], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.258 2.3.1.258] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6o07 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6o07 OCA], [http://pdbe.org/6o07 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6o07 RCSB], [http://www.ebi.ac.uk/pdbsum/6o07 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6o07 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/NAT5_YEAST NAT5_YEAST]] Non-essential component of the NatA N-terminal acetyltransferase, which catalyzes acetylation of proteins beginning with Met-Ser, Met-Gly and Met-Ala. N-acetylation plays a role in normal eukaryotic translation and processing, protect against proteolytic degradation and protein turnover. [[http://www.uniprot.org/uniprot/ARD1_YEAST ARD1_YEAST]] Catalytic component of the NatA N-terminal acetyltransferase, which catalyzes acetylation of proteins beginning with Met-Ser, Met-Gly and Met-Ala. N-acetylation plays a role in normal eukaryotic translation and processing, protect against proteolytic degradation and protein turnover.<ref>PMID:1600941</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Deng, S]] | ||
| + | [[Category: Marmorstein, R]] | ||
| + | [[Category: N-terminal acetylation]] | ||
| + | [[Category: Naa50]] | ||
| + | [[Category: Nata]] | ||
| + | [[Category: Nate]] | ||
| + | [[Category: Protein complex]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 05:42, 12 June 2019
Structure and mechanism of acetylation by the N-terminal dual enzyme NatA/Naa50 complex
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