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6q2w
From Proteopedia
(Difference between revisions)
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<StructureSection load='6q2w' size='340' side='right'caption='[[6q2w]], [[Resolution|resolution]] 1.99Å' scene=''> | <StructureSection load='6q2w' size='340' side='right'caption='[[6q2w]], [[Resolution|resolution]] 1.99Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6q2w]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Q2W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6Q2W FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6q2w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Q2W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6Q2W FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HBW:(2~{S})-1-[2,4-bis(chloranyl)-3-[[4-imidazol-1-yl-2-(trifluoromethyl)quinolin-8-yl]oxymethyl]phenyl]sulfonyl-~{N}-methyl-pyrrolidine-2-carboxamide'>HBW</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HBW:(2~{S})-1-[2,4-bis(chloranyl)-3-[[4-imidazol-1-yl-2-(trifluoromethyl)quinolin-8-yl]oxymethyl]phenyl]sulfonyl-~{N}-methyl-pyrrolidine-2-carboxamide'>HBW</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RORC, NR1F3, RORG, RZRG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6q2w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6q2w OCA], [http://pdbe.org/6q2w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6q2w RCSB], [http://www.ebi.ac.uk/pdbsum/6q2w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6q2w ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6q2w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6q2w OCA], [http://pdbe.org/6q2w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6q2w RCSB], [http://www.ebi.ac.uk/pdbsum/6q2w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6q2w ProSAT]</span></td></tr> | ||
</table> | </table> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Amaudrut, J]] | [[Category: Amaudrut, J]] | ||
| Line 27: | Line 29: | ||
[[Category: Barth, M]] | [[Category: Barth, M]] | ||
[[Category: Breinlinger, E C]] | [[Category: Breinlinger, E C]] | ||
| - | [[Category: Broqua, P]] | ||
[[Category: Calderwood, D J]] | [[Category: Calderwood, D J]] | ||
[[Category: Ciesielski, F]] | [[Category: Ciesielski, F]] | ||
| Line 35: | Line 36: | ||
[[Category: Potin, D]] | [[Category: Potin, D]] | ||
[[Category: Poupardin, O]] | [[Category: Poupardin, O]] | ||
| + | [[Category: Spitzer, L]] | ||
[[Category: Inverse agonist]] | [[Category: Inverse agonist]] | ||
[[Category: Nuclear hormone receptor]] | [[Category: Nuclear hormone receptor]] | ||
[[Category: Ror gamma]] | [[Category: Ror gamma]] | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
Revision as of 06:20, 12 June 2019
Crystal structure of human ROR gamma LBD in complex with a quinoline sulfonamide inverse agonist
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