4yqi
From Proteopedia
(Difference between revisions)
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==Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds== | ==Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds== | ||
| - | <StructureSection load='4yqi' size='340' side='right' caption='[[4yqi]], [[Resolution|resolution]] 1.92Å' scene=''> | + | <StructureSection load='4yqi' size='340' side='right'caption='[[4yqi]], [[Resolution|resolution]] 1.92Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4yqi]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YQI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YQI FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4yqi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Haein Haein]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YQI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YQI FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4GX:(4-AMINO-1,2,5-OXADIAZOL-3-YL)[4-(PYRIDIN-2-YLMETHYL)PIPERAZIN-1-YL]METHANONE'>4GX</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4GX:(4-AMINO-1,2,5-OXADIAZOL-3-YL)[4-(PYRIDIN-2-YLMETHYL)PIPERAZIN-1-YL]METHANONE'>4GX</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trmD, HI_0202 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=71421 HAEIN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_(guanine(37)-N(1))-methyltransferase tRNA (guanine(37)-N(1))-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.228 2.1.1.228] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_(guanine(37)-N(1))-methyltransferase tRNA (guanine(37)-N(1))-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.228 2.1.1.228] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yqi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yqi OCA], [http://pdbe.org/4yqi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4yqi RCSB], [http://www.ebi.ac.uk/pdbsum/4yqi PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yqi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yqi OCA], [http://pdbe.org/4yqi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4yqi RCSB], [http://www.ebi.ac.uk/pdbsum/4yqi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4yqi ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/TRMD_HAEIN TRMD_HAEIN]] Specifically methylates guanosine-37 in various tRNAs (By similarity).[HAMAP-Rule:MF_00605] | [[http://www.uniprot.org/uniprot/TRMD_HAEIN TRMD_HAEIN]] Specifically methylates guanosine-37 in various tRNAs (By similarity).[HAMAP-Rule:MF_00605] | ||
| + | |||
| + | ==See Also== | ||
| + | *[[TRNA methyltransferase|TRNA methyltransferase]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Haein]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Bonnette, W G]] | [[Category: Bonnette, W G]] | ||
[[Category: Elkins, P A]] | [[Category: Elkins, P A]] | ||
Revision as of 06:56, 12 June 2019
Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
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