6rwd
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of SjGST in complex with GSH and ellagic acid at 1.53 Angstrom resolution== | |
| - | + | <StructureSection load='6rwd' size='340' side='right'caption='[[6rwd]], [[Resolution|resolution]] 1.53Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6rwd]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RWD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6RWD FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=REF:2,3,7,8-TETRAHYDROXYCHROMENO[5,4,3-CDE]CHROMENE-5,10-DIONE'>REF</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ua5|1ua5]]</td></tr> |
| - | [[Category: Achilonu, I | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6rwd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rwd OCA], [http://pdbe.org/6rwd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rwd RCSB], [http://www.ebi.ac.uk/pdbsum/6rwd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rwd ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GST26_SCHJA GST26_SCHJA]] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. GST isoenzymes appear to play a central role in the parasite detoxification system. Other functions are also suspected including a role in increasing the solubility of haematin in the parasite gut. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Glutathione transferase]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Achilonu, I A]] | ||
| + | [[Category: Dirr, H W]] | ||
[[Category: Olfsen, J]] | [[Category: Olfsen, J]] | ||
| - | [[Category: Dirr, H.W]] | ||
[[Category: Pandian, R]] | [[Category: Pandian, R]] | ||
[[Category: Sayed, Y]] | [[Category: Sayed, Y]] | ||
| + | [[Category: Ellagic acid]] | ||
| + | [[Category: Gsh]] | ||
| + | [[Category: Schistosoma japonicum]] | ||
| + | [[Category: Sjgst]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 06:18, 19 June 2019
Crystal structure of SjGST in complex with GSH and ellagic acid at 1.53 Angstrom resolution
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