4z2b

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==The structure of human PDE12 residues 161-609 in complex with GSK3036342A==
==The structure of human PDE12 residues 161-609 in complex with GSK3036342A==
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<StructureSection load='4z2b' size='340' side='right' caption='[[4z2b]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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<StructureSection load='4z2b' size='340' side='right'caption='[[4z2b]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4z2b]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Z2B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Z2B FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4z2b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Z2B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Z2B FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4LC:3-(6-{[(2S,3S)-3-(HYDROXYMETHYL)-2-PHENYLMORPHOLIN-4-YL]CARBONYL}-1-METHYL-1H-BENZIMIDAZOL-2-YL)-1H-INDOLE-6-CARBONITRILE'>4LC</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4LC:3-(6-{[(2S,3S)-3-(HYDROXYMETHYL)-2-PHENYLMORPHOLIN-4-YL]CARBONYL}-1-METHYL-1H-BENZIMIDAZOL-2-YL)-1H-INDOLE-6-CARBONITRILE'>4LC</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4z0v|4z0v]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4z0v|4z0v]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PDE12 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4z2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4z2b OCA], [http://pdbe.org/4z2b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4z2b RCSB], [http://www.ebi.ac.uk/pdbsum/4z2b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4z2b ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4z2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4z2b OCA], [http://pdbe.org/4z2b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4z2b RCSB], [http://www.ebi.ac.uk/pdbsum/4z2b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4z2b ProSAT]</span></td></tr>
</table>
</table>
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</div>
</div>
<div class="pdbe-citations 4z2b" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4z2b" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Phosphodiesterase|Phosphodiesterase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Nolte, R T]]
[[Category: Nolte, R T]]
[[Category: Wang, L]]
[[Category: Wang, L]]

Revision as of 07:34, 19 June 2019

The structure of human PDE12 residues 161-609 in complex with GSK3036342A

PDB ID 4z2b

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