Enoyl-CoA hydratase
From Proteopedia
(Difference between revisions)
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<scene name='59/594523/Cv/2'>Rat ECH is homohexamer</scene>; <scene name='59/594523/Cv/3'>another view for homohexamer</scene>. ECH <scene name='59/594523/Cv/7'>active site binds the substrate analog hexadienoyl-CoA</scene>. <ref>PMID:12445775</ref> | <scene name='59/594523/Cv/2'>Rat ECH is homohexamer</scene>; <scene name='59/594523/Cv/3'>another view for homohexamer</scene>. ECH <scene name='59/594523/Cv/7'>active site binds the substrate analog hexadienoyl-CoA</scene>. <ref>PMID:12445775</ref> | ||
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| + | ==3D structures of enoyl-CoA hydratase== | ||
| + | [[Enoyl-CoA hydratase 3D structures]] | ||
</StructureSection> | </StructureSection> | ||
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**[[1iq6]] – ECH – ''Aeromonas punctata''<br /> | **[[1iq6]] – ECH – ''Aeromonas punctata''<br /> | ||
**[[5ve2]] – ECH – ''Pseudoalteromonas atlantica''<br /> | **[[5ve2]] – ECH – ''Pseudoalteromonas atlantica''<br /> | ||
| + | **[[5xzd]] – ECH – ''Roseovarius nubinhibens''<br /> | ||
*''Enoyl-CoA hydratase complexes'' | *''Enoyl-CoA hydratase complexes'' | ||
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**[[4kd6]] – ECH – ''Burkholderia graminis''<br /> | **[[4kd6]] – ECH – ''Burkholderia graminis''<br /> | ||
**[[3kqf]], [[3pea]] – ECH – ''Bacillus anthracis''<br /> | **[[3kqf]], [[3pea]] – ECH – ''Bacillus anthracis''<br /> | ||
| - | **[[3l3s]] – | + | **[[3l3s]], [[4izb]] – RpECH – ''Ruegeria pomeroyi''<br /> |
**[[3ot6]] – ECH – ''Pseudomonas syringae''<br /> | **[[3ot6]] – ECH – ''Pseudomonas syringae''<br /> | ||
**[[3lao]], [[5cpg]] – ECH – ''Pseudomonas aeruginosa''<br /> | **[[3lao]], [[5cpg]] – ECH – ''Pseudomonas aeruginosa''<br /> | ||
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**[[3qxz]], [[3r9q]] – ECH – ''Mycobacterium abscessus''<br /> | **[[3qxz]], [[3r9q]] – ECH – ''Mycobacterium abscessus''<br /> | ||
**[[4mou]] – ECH – ''Anthrobacter aurescens''<br /> | **[[4mou]] – ECH – ''Anthrobacter aurescens''<br /> | ||
| - | **[[4olq]] – ECH – ''Hyphomonas neptunium''<br /> | + | **[[4olq]], [[5c9g]] – ECH – ''Hyphomonas neptunium''<br /> |
**[[3i47]] – ECH – ''Legionella pneumophila''<br /> | **[[3i47]] – ECH – ''Legionella pneumophila''<br /> | ||
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**[[4fnd]] – MtECH + hydroxyhexanoyl-CoA<br /> | **[[4fnd]] – MtECH + hydroxyhexanoyl-CoA<br /> | ||
**[[3q0g]] – MtECH + butyryl-CoA + CoA<br /> | **[[3q0g]] – MtECH + butyryl-CoA + CoA<br /> | ||
| + | **[[4izd]], [[4izc]] – RpECH (mutant) + CoA derivative<br /> | ||
*Enoyl-CoA hydratase 1 | *Enoyl-CoA hydratase 1 | ||
Revision as of 08:38, 20 June 2019
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3D structures of enoyl-CoA hydratase
Updated on 20-June-2019
References
- ↑ Agnihotri G, Liu HW. Enoyl-CoA hydratase. reaction, mechanism, and inhibition. Bioorg Med Chem. 2003 Jan 2;11(1):9-20. PMID:12467702
- ↑ Sakai C, Yamaguchi S, Sasaki M, Miyamoto Y, Matsushima Y, Goto Y. ECHS1 mutations cause combined respiratory chain deficiency resulting in Leigh syndrome. Hum Mutat. 2015 Feb;36(2):232-9. doi: 10.1002/humu.22730. PMID:25393721 doi:http://dx.doi.org/10.1002/humu.22730
- ↑ Bell AF, Feng Y, Hofstein HA, Parikh S, Wu J, Rudolph MJ, Kisker C, Whitty A, Tonge PJ. Stereoselectivity of enoyl-CoA hydratase results from preferential activation of one of two bound substrate conformers. Chem Biol. 2002 Nov;9(11):1247-55. PMID:12445775
