Exoenzyme

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</StructureSection>
</StructureSection>
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==3D structures of exoenzyme==
 
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 
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{{#tree:id=OrganizedByTopic|openlevels=0|
 
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*Exoenzyme C3
 
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**[[1g24]] – CbExo residues 8-218 – ''Clostridium butulinum''<br />
 
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**[[1uzi]], [[1r45]], [[1r4b]], [[2c89]] – CbExo catalytic domain <br />
 
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**[[1gze]], [[2c8b]], [[2c8d]], [[2c8e]], [[2c8g]] – CbExo catalytic domain (mutant)<br />
 
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**[[3bw8]] - Exo catalytic domain - ''Clostridium limosum''<br />
 
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*Exoenzyme C3 complexes
 
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**[[1gzf]] – CbExo catalytic domain + pyridinium derivative + ADP + NAD<br />
 
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**[[2bov]] – CbExo + GDP + Ral-A GTPase<br />
 
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**[[2a78]] – CbExo catalytic domain + GDP + Ral-A GTPase<br />
 
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**[[2a9k]] – CbExo catalytic domain+ GDP + Ral-A GTPase + NAD<br />
 
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**[[2c8a]] – CbExo catalytic domain + nicotinamide<br />
 
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**[[2c8c]] – CbExo catalytic domain (mutant) + ADP + NAD<br />
 
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**[[2c8f]], [[2c8h]] – CbExo catalytic domain (mutant) + NAD<br />
 
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*Exoenzyme S
 
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**[[1r4t]] – PaExo S GAP domain – ''Pseudomonas aeruginosa'' - NMR<br />
 
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**[[1he1]] – PaExo S GAP domain + Ras-like protein + GDP <br />
 
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**[[1he9]] – PaExo S GAP domain + Ras-like protein <br />
 
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**[[6gn0]], [[6gn8]], [[6gnj]] – PaExo S residues 235-457 (mutant) + 14-3-3 protein β/α<br />
 
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**[[6gnk]] – PaExo S residues 235-457 (mutant) + 14-3-3 protein β/α + NAD derivative<br />
 
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**[[4zua]] – PaExo SA regulatory domain residues 2-178 <br />
 
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**[[3kxy]] – PaExo SC residues 1-133 + PaExo SE residues 16-81<br />
 
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*Exoenzyme T
 
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**[[4jmf]] – PaExo residues 28-77 + chaperone<br />
 
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**[[6jnp]] – PaExo residues 23-79 + YOPE rgulator<br />
 
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**[[6gnn]] – PaExo residues 235-457 + 14-3-3 protein β/α<br />
 
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}}
 
== References ==
== References ==

Revision as of 06:36, 25 June 2019

Structure of exoenzyme C3 catalytic domain complex with ADP and NAD (PDB code 2c8c).

Drag the structure with the mouse to rotate

References

  1. ↑ Han S, Arvai AS, Clancy SB, Tainer JA. Crystal structure and novel recognition motif of rho ADP-ribosylating C3 exoenzyme from Clostridium botulinum: structural insights for recognition specificity and catalysis. J Mol Biol. 2001 Jan 5;305(1):95-107. PMID:11114250 doi:10.1006/jmbi.2000.4292
  2. ↑ Menetrey J, Flatau G, Boquet P, Menez A, Stura EA. Structural basis for the NAD-hydrolysis mechanism and the ARTT-loop plasticity of C3 exoenzymes. Protein Sci. 2008 May;17(5):878-86. Epub 2008 Mar 27. PMID:18369192 doi:10.1110/ps.073398508

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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