Exotoxin

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Current revision (09:16, 25 June 2019) (edit) (undo)
 
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</StructureSection>
</StructureSection>
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==3D structures of exotoxin==
 
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 
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{{#tree:id=OrganizedByTopic|openlevels=0|
 
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*''Pseudomonas aeruginosa'' exotoxin
 
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**[[1ikq]] – PaET A <br />
 
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**[[1ikp]] – PaET A (mutant) <br />
 
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**[[6edg]] – PaET A domain III mutant) <br />
 
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**[[1dma]] – PaET A catalytic domain + nicotinamide + AMP <br />
 
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**[[1aer]] – PaET A catalytic domain + NAD analog + AMP <br />
 
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**[[1xk9]] – PaET A catalytic domain + inhibitor <br />
 
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**[[1zm2]] – PaET A catalytic domain + diphthamide + adenosine diphosphoribose + EF-2 <br />
 
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**[[1zm3]] – PaET A catalytic domain + diphthamide + EF-2 <br />
 
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**[[3b78]], [[2zit]] – PaET A catalytic domain + diphthamide + NAD + EF-2 <br />
 
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**[[3b82]], [[3b8h]] – PaET A catalytic domain (mutant) + diphthamide + NAD + EF-2 <br />
 
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**[[1zm4]] – PaET A catalytic domain + diphthamide + NAD analog + EF-2 <br />
 
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**[[1zm9]] – PaET A catalytic domain + diphthamide + inhibitor + EF-2 <br />
 
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*''Vibrio cholerae'' exotoxin
 
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**[[2q5t]] – VcET <br />
 
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**[[2q6m]], [[3ess]], [[3ki0]], [[3ki1]], [[3ki2]], [[3ki3]], [[3ki4]], [[3ki5]], [[3ki6]], [[3ki7]], [[3ny6]] – VcET catalytic domain + inhibitor <br />
 
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**[[3q9o]] – VcET + NAD <br />
 
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*''Streptococcus pyogenes'' exotoxin
 
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**[[1b1z]], [[1fnu]], [[1fnv]], [[1fnw]] – SpET A1 <br />
 
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**[[1dki]] – SpET B<br />
 
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**[[2jtc]] – SpET B (mutant) - NMR<br />
 
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**[[1an8]] – SpET C<br />
 
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**[[1et9]] – SpET H<br />
 
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**[[2ici]] – SpET I<br />
 
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**[[1ty0]] – SpET J<br />
 
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**[[1ha5]], [[1uup]] – SpET A1 + Zn<br />
 
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**[[1l0x]] – SpET A1 (mutant) + T cell receptor β chain<br />
 
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**[[1pvj]] – SpET B + inhibitor <br />
 
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**[[2uzj]] – SpET B + guanidine derivative <br />
 
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**[[1eu4]] – SpET H + Zn<br />
 
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**[[1ty2]] – SpET J + Zn<br />
 
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**[[1ktk]] – SpET C (mutant) + T cell receptor β chain<br />
 
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**[[1l0y]] – SpET A1 (mutant) + T cell receptor β chain + Zn<br />
 
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**[[1hqr]] – SpRT C + antibody + myelin basic protein<br />
 
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*''Staphylococcus aureus'' exotoxin
 
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**[[3ury]] – SaET <br />
 
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**[[1v1o]], [[1v1p]] – SaET 1 <br />
 
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**[[2r61]], [[2z8l]] – SaET 3<br />
 
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**[[3r2i]] – SaET 5<br />
 
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**[[4zys]] – SaET 6<br />
 
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**[[3o13]] – SaET 15<br />
 
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**[[3kls]] – SaET 1 (mutant) + complement C5<br />
 
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*''Corynebacterium diphtheriae'' exotoxin See [[Diphtheria toxin]]
 
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}}
 
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== References ==
== References ==

Current revision

Structure of Vibrio cholerae exotoxin complex with NAD and glycerol (PDB code 3q9o).

Drag the structure with the mouse to rotate

References

  1. Hamon MA, Batsche E, Regnault B, Tham TN, Seveau S, Muchardt C, Cossart P. Histone modifications induced by a family of bacterial toxins. Proc Natl Acad Sci U S A. 2007 Aug 14;104(33):13467-72. Epub 2007 Aug 3. PMID:17675409 doi:http://dx.doi.org/10.1073/pnas.0702729104
  2. Fieldhouse RJ, Jorgensen R, Lugo MR, Merrill AR. The 1.8 angstrom cholix toxin crystal structure in complex with NAD and evidence for a new kinetic model. J Biol Chem. 2012 Apr 25. PMID:22535961 doi:10.1074/jbc.M111.337311

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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