Exportin

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</StructureSection>
</StructureSection>
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==3D structures of exportin==
 
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 
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{{#tree:id=OrganizedByTopic|openlevels=0|
 
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*XPO-1
 
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**[[4bsm]], [[4bsn]] – hXPO – human<br />
 
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**[[1w9c]] – hXPO C terminal 6 heat repeats <br />
 
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**[[3vyc]] – yXPO (mutant) - yeast<br />
 
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**[[4fgv]] – XPO – ''Chaetomium thermophilum''<br />
 
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*XPO-1 complexes
 
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**[[3gb8]] – hXPO + RNA U transporter 1 <br />
 
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**[[3gjx]] – hXPO + RNA U transporter 1 + RAN<br />
 
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**[[5dis]] – hXPO + RAN + RNA U transporter 1 + MBP<br />
 
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**[[3m1i]], [[4gpt]], [[4gmx]], [[4hat]], [[4hb2]], [[5jlj]] – yXPO (mutant) + RAN + RANBP1 <br />
 
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**[[3wyf]] – yXPO + RAN + RANBP1 <br />
 
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**[[3wyg]] – yXPO + RAN + PKI-α<br />
 
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**[[5zpu]], [[5ytb]], [[5yst]], [[5uro]] - yXPO (mutant) + RAN + RANBP1 + GTP<br />
 
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**[[5ysu]] - yXPO (mutant) + RAN + RANBP1 + GTP + plumbagin<br />
 
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**[[4hau]], [[4hav]], [[4haw]], [[4hax]], [[4hay]], [[4haz]], [[4hb0]], [[4hb3]], [[4hb4]] – yXPO (mutant) + RAN + RANBP1 + antibiotic<br />
 
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**[[5dh9]], [[5dha]], [[5dhf]], [[5di9]], [[5uwj]], [[5dif]] - yXPO (mutant) + RAN + RANBP1 + signal peptide<br />
 
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**[[5uwo]], [[5uwp]], [[5uwq]], [[5uwr]], [[5uws]], [[5uwt]], [[5uwu]], [[5uww]], [[5uwi]], [[5uwh]] - yXPO + RAN + RANBP1 + signal peptide<br />
 
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**[[6cit]], [[6a38]] - yXPO + RAN + RANBP1 + NS2 peptide<br />
 
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**[[6a3a]], [[6a3b]], [[6a3c]], [[6a3e]] - yXPO (mutant) + RAN + RANBP1 + NS2 peptide<br />
 
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**[[5xoj]] - yXPO (mutant) + GSP1P + PKI-a + NUP42 peptide + GTP<br />
 
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**[[3nby]], [[3nbz]], [[3nc0]] – mXPO + RNA U transporter 1 + RANBP1 - mouse<br />
 
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**[[3nc1]] – mXPO + RANBP1<br />
 
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**[[2l1l]] – hXPO residues 504-630 + PKI-α - NMR<br />
 
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*XPO-t
 
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**[[3ibv]] – fyXPO – fission yeast<br />
 
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**[[3icq]] – fyXPO + RAN homolog + RNA <br />
 
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*XPO-4
 
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**[[5dlq]] – mXPO (mutant) + RAN + EIF5A1<br />
 
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*XPO-5
 
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**[[5yu7]] – hXPO <br />
 
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**[[5yu6]] – hXPO + peptide + RAN <br />
 
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**[[3a6p]] – hXPO + peptide + pre-microRNA <br />
 
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}}
 
== References ==
== References ==

Revision as of 09:39, 25 June 2019

Structure of yeast exportin-5 (magenta) complex with GTPaseRan (cyan), Mg+2 (green) and RNA (PDB code 3icq).

Drag the structure with the mouse to rotate

References

  1. ↑ Kohler A, Hurt E. Exporting RNA from the nucleus to the cytoplasm. Nat Rev Mol Cell Biol. 2007 Oct;8(10):761-73. PMID:17786152 doi:http://dx.doi.org/10.1038/nrm2255
  2. ↑ Cook AG, Fukuhara N, Jinek M, Conti E. Structures of the tRNA export factor in the nuclear and cytosolic states. Nature. 2009 Sep 3;461(7260):60-5. PMID:19680239 doi:10.1038/nature08394

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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