6jy5

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'''Unreleased structure'''
 
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The entry 6jy5 is ON HOLD until Paper Publication
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==Structure of CsoS4B from Halothiobacillus neapolitanus==
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<StructureSection load='6jy5' size='340' side='right'caption='[[6jy5]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6jy5]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JY5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JY5 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6jy5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jy5 OCA], [http://pdbe.org/6jy5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jy5 RCSB], [http://www.ebi.ac.uk/pdbsum/6jy5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jy5 ProSAT]</span></td></tr>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Carboxysome, encapsulating an enzymatic core within an icosahedral-shaped semipermeable protein shell, could enhance CO2 fixation under low CO2 conditions in the environment. The shell of Halothiobacillus neapolitanus alpha-carboxysome possesses two 38% sequence-identical pentameric proteins, namely CsoS4A and CsoS4B. However, the functions of two paralogous pentameric proteins in alpha-carboxysome assembly remain unknown. Here we report the crystal structure of CsoS4B at 2.15A resolution. It displays as a stable pentamer, each subunit of which consists of a beta-barrel core domain, in addition to an insertion of helix alpha1 that forms the central pore. Structural comparisons and multiple-sequence alignment strongly indicate that CsoS4A and CsoS4B differ from each other in interacting with various components of alpha-carboxysome, despite they share a similar overall structure. These findings provide the structural basis for further investigations on the self-assembly process of carboxysome.
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Authors: Zhao, Y.Y., Jiang, Y.L., Chen, Y., Zhou, C.Z., Li, Q.
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Crystal structure of pentameric shell protein CsoS4B of Halothiobacillus neapolitanus alpha-carboxysome.,Zhao YY, Jiang YL, Chen Y, Zhou CZ, Li Q Biochem Biophys Res Commun. 2019 Jul 30;515(3):510-515. doi:, 10.1016/j.bbrc.2019.05.047. Epub 2019 Jun 3. PMID:31171360<ref>PMID:31171360</ref>
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Description: Structure of CsoS4B from Halothiobacillus neapolitanus
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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[[Category: Unreleased Structures]]
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</div>
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[[Category: Zhao, Y.Y]]
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<div class="pdbe-citations 6jy5" style="background-color:#fffaf0;"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Chen, Y]]
[[Category: Chen, Y]]
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[[Category: Jiang, Y.L]]
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[[Category: Jiang, Y L]]
[[Category: Li, Q]]
[[Category: Li, Q]]
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[[Category: Zhou, C.Z]]
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[[Category: Zhao, Y Y]]
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[[Category: Zhou, C Z]]
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[[Category: Carboxysome shell protein]]
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[[Category: Pentameric protein]]
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[[Category: Structural protein]]

Revision as of 06:54, 26 June 2019

Structure of CsoS4B from Halothiobacillus neapolitanus

PDB ID 6jy5

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