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5a28

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==Leishmania major N-myristoyltransferase in complex with a chlorophenyl inhibitor (compound 13).==
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==Leishmania major N-myristoyltransferase in complex with a chlorophenyl 1,3,4-oxadiazole inhibitor.==
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<StructureSection load='5a28' size='340' side='right' caption='[[5a28]], [[Resolution|resolution]] 1.48&Aring;' scene=''>
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<StructureSection load='5a28' size='340' side='right'caption='[[5a28]], [[Resolution|resolution]] 1.48&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5a28]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A28 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A28 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5a28]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Leima Leima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A28 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A28 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MYA:TETRADECANOYL-COA'>MYA</scene>, <scene name='pdbligand=TUQ:4-(4-CHLORO-2-{5-[(TRIMETHYL-1H-PYRAZOL-4-YL)METHYL]-1,3,4-OXADIAZOL-2-YL}PHENOXY)PIPERIDINE'>TUQ</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MYA:TETRADECANOYL-COA'>MYA</scene>, <scene name='pdbligand=TUQ:4-(4-CHLORO-2-{5-[(TRIMETHYL-1H-PYRAZOL-4-YL)METHYL]-1,3,4-OXADIAZOL-2-YL}PHENOXY)PIPERIDINE'>TUQ</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5a27|5a27]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5a27|5a27]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glycylpeptide_N-tetradecanoyltransferase Glycylpeptide N-tetradecanoyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.97 2.3.1.97] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glycylpeptide_N-tetradecanoyltransferase Glycylpeptide N-tetradecanoyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.97 2.3.1.97] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a28 OCA], [http://pdbe.org/5a28 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5a28 RCSB], [http://www.ebi.ac.uk/pdbsum/5a28 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a28 OCA], [http://pdbe.org/5a28 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5a28 RCSB], [http://www.ebi.ac.uk/pdbsum/5a28 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5a28 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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</StructureSection>
</StructureSection>
[[Category: Glycylpeptide N-tetradecanoyltransferase]]
[[Category: Glycylpeptide N-tetradecanoyltransferase]]
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[[Category: Large Structures]]
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[[Category: Leima]]
[[Category: Barker, K V]]
[[Category: Barker, K V]]
[[Category: Brannigan, J A]]
[[Category: Brannigan, J A]]

Revision as of 08:14, 26 June 2019

Leishmania major N-myristoyltransferase in complex with a chlorophenyl 1,3,4-oxadiazole inhibitor.

PDB ID 5a28

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