4zsp
From Proteopedia
(Difference between revisions)
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==BACE crystal structure with bicyclic aminothiazine inhibitor== | ==BACE crystal structure with bicyclic aminothiazine inhibitor== | ||
| - | <StructureSection load='4zsp' size='340' side='right' caption='[[4zsp]], [[Resolution|resolution]] 1.91Å' scene=''> | + | <StructureSection load='4zsp' size='340' side='right'caption='[[4zsp]], [[Resolution|resolution]] 1.91Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4zsp]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZSP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZSP FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4zsp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZSP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZSP FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4RZ:N-[(4AS,6S,8AR)-2-AMINO-4A,5,6,7,8,8A-HEXAHYDRO-4H-3,1-BENZOTHIAZIN-6-YL]-3-CHLOROBENZAMIDE'>4RZ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4RZ:N-[(4AS,6S,8AR)-2-AMINO-4A,5,6,7,8,8A-HEXAHYDRO-4H-3,1-BENZOTHIAZIN-6-YL]-3-CHLOROBENZAMIDE'>4RZ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4zsm|4zsm]], [[4zsq|4zsq]], [[4zsr|4zsr]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4zsm|4zsm]], [[4zsq|4zsq]], [[4zsr|4zsr]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BACE1, BACE, KIAA1149 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Memapsin_2 Memapsin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.46 3.4.23.46] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Memapsin_2 Memapsin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.46 3.4.23.46] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zsp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zsp OCA], [http://pdbe.org/4zsp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zsp RCSB], [http://www.ebi.ac.uk/pdbsum/4zsp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4zsp ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zsp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zsp OCA], [http://pdbe.org/4zsp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zsp RCSB], [http://www.ebi.ac.uk/pdbsum/4zsp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4zsp ProSAT]</span></td></tr> | ||
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</div> | </div> | ||
<div class="pdbe-citations 4zsp" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 4zsp" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Beta secretase 3D structures|Beta secretase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
[[Category: Timm, D E]] | [[Category: Timm, D E]] | ||
Revision as of 08:51, 26 June 2019
BACE crystal structure with bicyclic aminothiazine inhibitor
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