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Ferritin

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Line 19: Line 19:
==3D Structures of Ferritin==
==3D Structures of Ferritin==
 +
[[Ferritin 3D structures]]
</StructureSection>
</StructureSection>
 +
 +
==3D Structures of Ferritin==
 +
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|
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**[[3a9q]] - soFR from gene SferH4 (mutant) <br />
**[[3a9q]] - soFR from gene SferH4 (mutant) <br />
**[[3egm]], [[3bve]], [[3bvf]], [[3bvi]], [[3bvk]], [[3bvl]] – HpFR – ''Heliobacter pylori''<br />
**[[3egm]], [[3bve]], [[3bvf]], [[3bvi]], [[3bvk]], [[3bvl]] – HpFR – ''Heliobacter pylori''<br />
 +
**[[5c6f]] – HpFR (mutant) + Fe <br />
**[[1z4a]], [[1vlg]] – FR – ''Thermotoga maritime''<br />
**[[1z4a]], [[1vlg]] – FR – ''Thermotoga maritime''<br />
**[[1s3q]], [[1sq3]], [[3kx9]], [[5v5k]] – FR – ''Archaeoglubus fulgidus''<br />
**[[1s3q]], [[1sq3]], [[3kx9]], [[5v5k]] – FR – ''Archaeoglubus fulgidus''<br />
Line 38: Line 43:
**[[3vnx]] – FR – ''Ulva pertusa''<br />
**[[3vnx]] – FR – ''Ulva pertusa''<br />
**[[4ism]], [[4isp]], [[4itt]], [[4itw]], [[4iwj]], [[4iwk]], [[4ixk]], [[3e6r]], [[3e6s]] – PnmFR – ''Pseudo-nitschia multiseries''<br />
**[[4ism]], [[4isp]], [[4itt]], [[4itw]], [[4iwj]], [[4iwk]], [[4ixk]], [[3e6r]], [[3e6s]] – PnmFR – ''Pseudo-nitschia multiseries''<br />
 +
**[[4zkh]], [[4zkw]], [[4zkx]], [[4zl5]], [[4zl6]], [[4zlw]], [[4zmc]] – PnmFR (mutant) + Fe<br />
**[[1z6o]] – FR – ''Trichoplusia ni''<br />
**[[1z6o]] – FR – ''Trichoplusia ni''<br />
**[[5n5f]] – FR – ''Haliangium ochraceum''<br />
**[[5n5f]] – FR – ''Haliangium ochraceum''<br />
 +
**[[5ouz]], [[5ouw]] – SyFR – ''Synechococcus''<br />
 +
**[[6gkc]], [[6gka]] – SyFR + Fe <br />
 +
**[[6gkb]] – SyFR (mutant) + Fe <br />
 +
**[[6a4u]] – FR (mutant) – ''Marsupenaeus japonicus'' <br />
 +
**[[4reu]] – EcFR + Fe<br />
 +
**[[4xgs]] – EcFR (mutant) + Fe2O2<br />
 +
**[[4ztt]] – EcFR (mutant) + Fe2O + Fe2 + Fe + O2<br />
 +
**[[4cmy]] – FR + Fe – ''Chlorobaculum tepidum''<br />
*Ferritin light chain (FTL)
*Ferritin light chain (FTL)
-
**[[1lb3]], [[1h96]] – mFTL – mouse<br />
+
**[[1fha]], [[5lg8]] - hFTL+ Fe - human<br />
-
**[[3noz]], [[3np0]], [[3np2]], [[3o7r]] – hoFTL (mutant) - horse<br />
+
**[[3o7s]], [[3u90]], [[6msx]], [[6gxj]] – hoFTL - horse<br />
-
**[[3o7s]], [[3u90]] - hoFTL<br />
+
**[[4v1w]], [[6rjh]] – hoFTL – cryo EM<br />
-
**[[4v1w]] – hoFTL – cryo EM<br />
+
**[[3noz]], [[3np0]], [[3np2]], [[3o7r]] – hoFTL (mutant) <br />
 +
**[[5lg2]] - hoFTL + Fe<br />
 +
**[[5czu]] - hoFTL (mutant) + Fe<br />
**[[3rav]], [[3rd0]] – hoFTL + barbiturate
**[[3rav]], [[3rd0]] – hoFTL + barbiturate
 +
**[[1lb3]], [[1h96]] – mFTL – mouse<br />
*Ferritin middle subunit (FTM)
*Ferritin middle subunit (FTM)
Line 54: Line 71:
**[[4p18]], [[5xhi]], [[5xhm]], [[5xhn]], [[5xho]] – bFTM (mutant) <br />
**[[4p18]], [[5xhi]], [[5xhm]], [[5xhn]], [[5xho]] – bFTM (mutant) <br />
**[[4lpj]], [[4lqj]], [[6i36]], [[4lqv]], [[4lyu]], [[4lyx]], [[4my7]], [[3rbc]], [[3rgd]] – bFTM + Fe <br />
**[[4lpj]], [[4lqj]], [[6i36]], [[4lqv]], [[4lyu]], [[4lyx]], [[4my7]], [[3rbc]], [[3rgd]] – bFTM + Fe <br />
-
**[[4mjy]], [[4ml5]], [[4mn9]], [[5j8w]], [[5j93]], [[5j9v]], [[5jac]] – bFTM (mutant) + Fe<br />
+
**[[4mjy]], [[4ml5]], [[4mn9]], [[5j8w]], [[5j93]], [[5j9v]], [[5jac]], [[6iaj]], [[6iaf]], [[6i9t]], [[6i9p]] – bFTM (mutant) + Fe<br />
**[[4lqh]], [[1mfr]], [[3ka3]] – bFTM + Mg<br />
**[[4lqh]], [[1mfr]], [[3ka3]] – bFTM + Mg<br />
**[[4lpm]], [[4mku]], [[5j8s]], [[3se1]], [[3sh6]], [[3shx]] – bFTM (mutant) + Mg<br />
**[[4lpm]], [[4mku]], [[5j8s]], [[3se1]], [[3sh6]], [[3shx]] – bFTM (mutant) + Mg<br />
Line 64: Line 81:
*Ferritin heavy subunit (FTH)
*Ferritin heavy subunit (FTH)
-
**[[2z6m]], [[1r03]], [[2fha]], [[5yi5]] – hFTH<br />
+
**[[5gou]], [[5yi5]] – hFTH <br />
-
**[[5xb1]] – hFTH (mutant)<br />
+
**[[5xb1]], [[6ipc]], [[5znd]] – hFTH (mutant)<br />
 +
**[[4oyn]], [[4y08]], [[4zjk]], [[5jkk]], [[5jkl]], [[5jkm]], [[6b8g]], [[6b8f]], [[4ykh]] – hFTH + Fe<br />
 +
**[[6ipp]] – hFTH (mutant) + Fe<br />
 +
**[[3wnw]] – mFTL + Fe<br />
 +
**[[5obA]] – mFTL (mutant) + Fe<br />
**[[2z6o]] – FTH – ''Trichoplusia ni''<br />
**[[2z6o]] – FTH – ''Trichoplusia ni''<br />
*apo-ferritin (apo-FR)
*apo-ferritin (apo-FR)
-
**[[2x17]] – apo-PfFR+Ag <br />
+
**[[2clu]], [[2cn6]] - apo-hFR (mutant)+Zn <br />
-
**[[2jd8]] – apo-PfFR+Zn<br />
+
**[[3h7g]] – apo-hoFR+Au <br />
**[[3h7g]] – apo-hoFR+Au <br />
**[[1hrs]] - apo-hoFR+protoporphyrin<br />
**[[1hrs]] - apo-hoFR+protoporphyrin<br />
-
**[[5c6f]] – apo-HpFR (mutant) + Fe <br />
 
-
**[[2clu]], [[2cn6]] - apo-hFR (mutant)+Zn - human<br />
 
-
**[[4reu]] – apo-EcFR + Fe<br />
 
-
**[[4xgs]] – apo-EcFR (mutant) + Fe2O2<br />
 
-
**[[4ztt]] – apo-EcFR (mutant) + Fe2O + Fe2 + Fe + O2<br />
 
-
**[[4zkh]], [[4zkw]], [[4zkx]], [[4zl5]], [[4zl6]], [[4zlw]], [[4zmc]] – PnmFR (mutant) + Fe<br />
 
-
**[[4cmy]] – FR + Fe – ''Chlorobaculum tepidum''<br />
 
**[[5wpn]] - apo-FR (mutant)+Zn – parchment tube worm<br />
**[[5wpn]] - apo-FR (mutant)+Zn – parchment tube worm<br />
 +
**[[2x17]] – apo-PfFR+Ag <br />
 +
**[[2jd8]] – apo-PfFR+Zn<br />
*apo-ferritin light chain (apo-FTL)
*apo-ferritin light chain (apo-FTL)
 +
**[[2fg8]] – apo-hFTL + Cs<br />
 +
**[[3kxu]], [[2ffx]], [[2fg4]] - apo-hFTL+ Cd<br />
**[[2zg7]], [[2z5p]], [[2z5q]], [[2z5r]], [[3fi6]], [[3af7]], [[5e2d]], [[5hqo]] – apo-hoFTL+Pd<br />
**[[2zg7]], [[2z5p]], [[2z5q]], [[2z5r]], [[3fi6]], [[3af7]], [[5e2d]], [[5hqo]] – apo-hoFTL+Pd<br />
**[[2zg8]], [[2zg9]], [[3af8]], [[3af9]], [[3noz]], [[3np0]], [[3np2]] - apo-hoFTL (mutant)+Pd<br />
**[[2zg8]], [[2zg9]], [[3af8]], [[3af9]], [[3noz]], [[3np0]], [[3np2]] - apo-hoFTL (mutant)+Pd<br />
Line 93: Line 110:
**[[4z3b]] - apo-hoFTL + Mn<br />
**[[4z3b]] - apo-hoFTL + Mn<br />
**[[5axs]], [[5e1u]], [[5erj]], [[5erk]], [[5ix6]], [[5mij]], [[5mik]], [[2w0o]], [[3f32]], [[1ies]], [[1ier]], [[1dat]], [[1aew]], [[2g4h]], [[2za6]] - apo-hoFTL + Cd<br />
**[[5axs]], [[5e1u]], [[5erj]], [[5erk]], [[5ix6]], [[5mij]], [[5mik]], [[2w0o]], [[3f32]], [[1ies]], [[1ier]], [[1dat]], [[1aew]], [[2g4h]], [[2za6]] - apo-hoFTL + Cd<br />
-
**[[5lg2]] - apo-hoFTL + Fe<br />
+
**[[6hju]], [[6hjt]] – apo-hoFTL + Pt<br />
-
**[[5czu]] - apo-hoFTL (mutant) + Fe<br />
+
**[[6fj9]], [[6fx8]], [[6enw]], [[6env]] – apo-hoFTL + Au<br />
**[[3f33]], [[3f34]], [[3f35]], [[3f36]], [[3f37]], [[3f38]], [[3f39]] - apo-hoFTL+phenols<br />
**[[3f33]], [[3f34]], [[3f35]], [[3f36]], [[3f37]], [[3f38]], [[3f39]] - apo-hoFTL+phenols<br />
**[[2v2i]], [[2v2j]] - apo-hoFTL+haemin<br />
**[[2v2i]], [[2v2j]] - apo-hoFTL+haemin<br />
Line 111: Line 128:
*apo-ferritin heavy chain (apo-FTH)
*apo-ferritin heavy chain (apo-FTH)
-
**[[2za7]], [[2za8]] - apo-hoFTH (mutant) + Cd<br />
 
-
**[[5gu0]], [[5gu1]], [[5gu2]], [[5gu3]] - apo-hoFTH (mutant) + Cd<br />
 
**[[3erz]] – apo-hFTH+Hg<br />
**[[3erz]] – apo-hFTH+Hg<br />
**[[3es3]] - apo-hFTH+Au<br />
**[[3es3]] - apo-hFTH+Au<br />
-
**[[6b8f]], [[4ykh]] – apo-hFTH+Fe<br />
+
**[[5z91]], [[5z8s]], [[5z8j]] - apo-hFTH (mutant) +Au<br />
**[[5vtd]] – apo-hFTH+ Co<br />
**[[5vtd]] – apo-hFTH+ Co<br />
**[[5up7]] – apo-hFTH+ Ni<br />
**[[5up7]] – apo-hFTH+ Ni<br />
**[[5n26]] – apo-hFTH+ Pt<br />
**[[5n26]] – apo-hFTH+ Pt<br />
-
**[[5n27]] – apo-hFTH+ Mg<br />
+
**[[6ftv]] – apo-hFTH + Ru<br />
-
**[[2cn7]] – apo-hFTH (mutant) + Ca<br />
+
**[[2fha]] – apo-hFTH + Ca<br />
-
**[[2chi]], [[2clu]], [[2cei]], [[2cih]], [[2cn6]], [[2iu2]] – apo-hFTH (mutant) + Zn<br />
+
**[[2cn7]], [[2fha]] – apo-hFTH (mutant) + Ca<br />
-
**[[5up8]], [[5up9]] – apo-hFTH+ Zn + oxamate derivative<br />
+
-
**[[4oyn]], [[4y08]], [[4zjk]], [[5jkk]], [[5jkl]], [[5jkm]] – hFTH + Fe<br />
+
**[[2z6m]] – hFTH + Zn<br />
**[[2z6m]] – hFTH + Zn<br />
-
**[[5cmq]], [[5cmr]] - hFTH (mutant) + Zn<br />
+
**[[2chi]], [[2clu]], [[2cei]], [[2cih]], [[2cn6]], [[2iu2]], [[5cmq]], [[5cmr]], [[2z6m]] – apo-hFTH (mutant) + Zn<br />
-
**[[1r03]], [[3ajo]] – hFTH + Mg<br />
+
**[[5up8]], [[5up9]] – apo-hFTH+ Zn + oxamate derivative<br />
-
**[[2fha]] – hFTH + Ca<br />
+
**[[1r03]], [[3ajo]], [[5n27]] – hFTH + Mg<br />
-
**[[4dyx]], [[4dyy]], [[4dyz]], [[4dz0]] - hFTH (mutant) + Cu<br />
+
**[[3ajp]], [[3ajq]], [[6ipq]], [[6ipo]], [[5z8u]] - hFTH (mutant) + Mg<br />
-
**[[3ajp]], [[3ajq]] - hFTH (mutant) + Mg<br />
+
**[[4dyx]], [[4dyy]], [[4dyz]], [[4dz0]] – apo-hFTH (mutant) + Cu<br />
-
**[[3wnw]] – mFTH + Fe<br />
+
**[[5gu0]], [[5gu1]], [[5gu2]], [[5gu3]], [[2za7]], [[2za8]] - apo-hoFTH (mutant) + Cd<br />
 +
**[[5obb]] – mFTL + Tb<br />
*Ferritin light+heavy chains
*Ferritin light+heavy chains
Line 136: Line 150:
**[[5gn8]] – hFTH + Ca<br />
**[[5gn8]] – hFTH + Ca<br />
-
*Bacterioferritin (BFR)
+
*Bacterioferritin (BFR) 0r ferroxidase
**[[3gvy]] – BFR – ''Rhodobacter sphaeroides''<br />
**[[3gvy]] – BFR – ''Rhodobacter sphaeroides''<br />
Line 146: Line 160:
**[[2wtl]], [[3qb9]], [[3uof]], [[3uoi]] – BFR – ''Mycobacterium tuberculosis''<br />
**[[2wtl]], [[3qb9]], [[3uof]], [[3uoi]] – BFR – ''Mycobacterium tuberculosis''<br />
**[[3bkn]] - MsBFR – ''Mycobacterium smegmatis''<br />
**[[3bkn]] - MsBFR – ''Mycobacterium smegmatis''<br />
-
**[[3is7]], [[3is8]], [[3ise]], [[3isf]], [[3r2h]], [[3r2k]], [[3r2l]], [[3r2m]], [[3r2o]], [[3r2r]], [[3r2s]] – BFR – ''Pseudomonas aeruginosa''<br />
+
**[[3is7]], [[3is8]], [[3ise]], [[3isf]], [[3r2h]], [[3r2k]], [[3r2l]], [[3r2m]], [[3r2o]], [[3r2r]], [[3r2s]], [[6nlf]], [[5d8o]] – PaBFR – ''Pseudomonas aeruginosa''<br />
 +
**[[5d8x]], [[5d8s]], [[5d8r]], [[5d8q]], [[4tog]], [[4tof]], [[4tod]], [[4tob]], [[4to9]] - PaBFR (mutant) <br />
 +
**[[5d8p]] - PaBFR + Fe<br />
 +
**[[5d8y]], [[4toh]], [[4toe]], [[4toc]], [[4toa]] - PaBFR (mutant) + Fe<br />
 +
**[[6nli]], [[6nlk]], [[6nll]], [[6nlm]], [[6nln]] - PaBFR + inhibitor<br />
 +
**[[6nlg]] - PaBFR (mutant) + inhibitor<br />
 +
**[[4E6K]] - PaBFR + BFR-associated protein<br />
**[[1bfr]], [[1bcf]], [[2htn]], [[2vxi]], [[3e1j]], [[3e1l]], [[3e1m]], [[3e1n]], [[3e1p]], [[3e1o]], [[3e1q]], [[2y3q]] – EcBFR <br />
**[[1bfr]], [[1bcf]], [[2htn]], [[2vxi]], [[3e1j]], [[3e1l]], [[3e1m]], [[3e1n]], [[3e1p]], [[3e1o]], [[3e1q]], [[2y3q]] – EcBFR <br />
 +
**[[4xku]], [[4xkt]], [[4xks]], [[4u3g]] - EcBFR (mutant) <br />
**[[3e2c]], [[4cvr]], [[4cvt]] – EcBFR (mutant) + Zn<br />
**[[3e2c]], [[4cvr]], [[4cvt]] – EcBFR (mutant) + Zn<br />
**[[4cvp]], [[3ghq]] - EcBFR (mutant) + Fe<br />
**[[4cvp]], [[3ghq]] - EcBFR (mutant) + Fe<br />
**[[4cvs]] – EcBFR (mutant) + Cd<br />
**[[4cvs]] – EcBFR (mutant) + Cd<br />
-
**[[4am2]], [[4am4]], [[4am5]] – BFR + Fe – ''Blastochloris viridis''
+
**[[4am2]], [[4am4]], [[4am5]] – BFR + Fe – ''Blastochloris viridis''<br />
 +
**[[5zur]] - BFR + Fe - ''Achromobacter''<br />
 +
**[[5xx9]] - BFR + Fe – ''Streptomyces coelicolor''<br />
*Thioferritin (TFR)
*Thioferritin (TFR)
Line 163: Line 186:
**[[2iy4]] – Dps + Fe – ''Listeria monocytogenes''<br />
**[[2iy4]] – Dps + Fe – ''Listeria monocytogenes''<br />
**[[2bkc]], [[2bk6]], [[2bjy]] – LiDps (mutant) <br />
**[[2bkc]], [[2bk6]], [[2bjy]] – LiDps (mutant) <br />
 +
**[[6hv1]] – Dps – ''Listeria innocua''<br />
**[[2f7n]] – Dps + Co – ''Deinococcus radiodurans''<br />
**[[2f7n]] – Dps + Co – ''Deinococcus radiodurans''<br />
**[[4a25]] - Dps + Mn – ''Kinecoccus radiodurans''<br />
**[[4a25]] - Dps + Mn – ''Kinecoccus radiodurans''<br />
**[[1tjo]], [[1tk6]], [[1tkp]], [[1tko]], [[1moj]] – Dps + Fe – ''Halobacterium salinarum''<br />
**[[1tjo]], [[1tk6]], [[1tkp]], [[1tko]], [[1moj]] – Dps + Fe – ''Halobacterium salinarum''<br />
**[[1o9r]] – Dps + Fe – ''Agrobacterium tumefaciens''<br />
**[[1o9r]] – Dps + Fe – ''Agrobacterium tumefaciens''<br />
-
**[[1dps]], [[1f33]] – EcDps <br />
+
**[[1dps]], [[1f33]], [[5xgo]] – EcDps <br />
**[[1f30]] – EcDps + Zn<br />
**[[1f30]] – EcDps + Zn<br />
**[[1jre]] – EcDps + Cd<br />
**[[1jre]] – EcDps + Cd<br />

Revision as of 08:20, 30 June 2019

Crystal structure of Fe-soaked ferritin from the hyperthermophilic archael anaerobe Pyrococcus furiousus 2jd7

Drag the structure with the mouse to rotate

3D Structures of Ferritin

Updated on 30-June-2019

References

  1. ↑ Wang W, Knovich MA, Coffman LG, Torti FM, Torti SV. Serum ferritin: Past, present and future. Biochim Biophys Acta. 2010 Aug;1800(8):760-9. doi: 10.1016/j.bbagen.2010.03.011. , Epub 2010 Mar 19. PMID:20304033 doi:http://dx.doi.org/10.1016/j.bbagen.2010.03.011

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman, David Canner, Eran Hodis, Alexander Berchansky

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