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6n8w
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of Unliganded Hsp90-Beta N-Terminal Domain== | |
| - | + | <StructureSection load='6n8w' size='340' side='right'caption='[[6n8w]], [[Resolution|resolution]] 3.09Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6n8w]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N8W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6N8W FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6n8w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n8w OCA], [http://pdbe.org/6n8w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6n8w RCSB], [http://www.ebi.ac.uk/pdbsum/6n8w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6n8w ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/HS90B_HUMAN HS90B_HUMAN]] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.<ref>PMID:16478993</ref> <ref>PMID:19696785</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Gewirth, D T]] | ||
| + | [[Category: Huck, J D]] | ||
| + | [[Category: Que, N L.S]] | ||
| + | [[Category: Chaperone]] | ||
| + | [[Category: Cytosolic]] | ||
| + | [[Category: Heat-shock]] | ||
| + | [[Category: Hsp90]] | ||
Revision as of 05:54, 3 July 2019
Structure of Unliganded Hsp90-Beta N-Terminal Domain
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Categories: Large Structures | Gewirth, D T | Huck, J D | Que, N L.S | Chaperone | Cytosolic | Heat-shock | Hsp90
