6roi
From Proteopedia
(Difference between revisions)
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- | '''Unreleased structure''' | ||
- | + | ==Cryo-EM structure of the partially activated Drs2p-Cdc50p== | |
- | + | <StructureSection load='6roi' size='340' side='right'caption='[[6roi]], [[Resolution|resolution]] 3.70Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[6roi]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ROI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ROI FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2Y5:(2R)-1-{[(R)-HYDROXY{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-TETRAHYDROXY-4-(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL]OXY}-3-(OCTADECANOYLOXY)PROPAN-2-YL+(5Z,8Z,11Z,14Z)-ICOSA-5,8,11,14-TETRAENOATE'>2Y5</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |
- | [[Category: | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BFD:ASPARTATE+BERYLLIUM+TRIFLUORIDE'>BFD</scene></td></tr> |
+ | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/P-type_phospholipid_transporter P-type phospholipid transporter], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=7.6.2.1 7.6.2.1] </span></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6roi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6roi OCA], [http://pdbe.org/6roi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6roi RCSB], [http://www.ebi.ac.uk/pdbsum/6roi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6roi ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/ATC3_YEAST ATC3_YEAST]] This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of phospholipids (Potential). Seems to be involved in ribosome assembly. [[http://www.uniprot.org/uniprot/CDC50_YEAST CDC50_YEAST]] Required for polarized cell growth. | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: P-type phospholipid transporter]] | ||
+ | [[Category: Ash, M R]] | ||
+ | [[Category: Boesen, T]] | ||
+ | [[Category: Dieudonne, T]] | ||
+ | [[Category: Januliene, D]] | ||
+ | [[Category: Karlsen, J L]] | ||
+ | [[Category: Kuhlbrandt, W]] | ||
+ | [[Category: Lenoir, G]] | ||
+ | [[Category: Lyons, J A]] | ||
+ | [[Category: Moeller, A]] | ||
+ | [[Category: Montigny, C]] | ||
+ | [[Category: Nissen, P]] | ||
+ | [[Category: Timcenko, M]] | ||
+ | [[Category: Ulstrup, J J]] | ||
+ | [[Category: Lipid flippase]] | ||
+ | [[Category: Lipid transport]] | ||
+ | [[Category: P-type atpase]] | ||
+ | [[Category: Ps transport]] |
Revision as of 06:11, 3 July 2019
Cryo-EM structure of the partially activated Drs2p-Cdc50p
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Categories: Large Structures | P-type phospholipid transporter | Ash, M R | Boesen, T | Dieudonne, T | Januliene, D | Karlsen, J L | Kuhlbrandt, W | Lenoir, G | Lyons, J A | Moeller, A | Montigny, C | Nissen, P | Timcenko, M | Ulstrup, J J | Lipid flippase | Lipid transport | P-type atpase | Ps transport