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Lignin peroxidase

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== Structural highlights ==
== Structural highlights ==
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*<scene name='48/486472/Cv/3'>Heme binding site</scene>.
+
*<scene name='48/486472/Cv/8'>Heme binding site</scene>. Water molecules are shown as red spheres.
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*<scene name='48/486472/Cv/4'>Fe coordination site</scene>.
+
*<scene name='48/486472/Cv/9'>Fe coordination site</scene>.
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*<scene name='48/486472/Cv/5'>Cl coordination site</scene>.
+
*<scene name='48/486472/Cv/10'>Cl coordination site</scene>.
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*<scene name='48/486472/Cv/6'>1st Ca coordination site</scene>.
+
*<scene name='48/486472/Cv/13'>1st Ca coordination site</scene>.
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*<scene name='48/486472/Cv/7'>2nd Ca coordination site</scene>.
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*<scene name='48/486472/Cv/14'>2nd Ca coordination site</scene>.
</StructureSection>
</StructureSection>
==3D structures of lignin peroxidase==
==3D structures of lignin peroxidase==

Revision as of 10:36, 8 July 2019

Lignin peroxidase containing heme complex with MPD, Ca+2 (large green), Na+ (purple) and Cl- (small green) ions (PDB entry 3q3u)

Drag the structure with the mouse to rotate

3D structures of lignin peroxidase

1lga, 1llp, 1qpa, 1b80, 1b82 – PcLip – Phanerochaete chrysosporium
1b85 – PcLip (mutant)
3q3u – Lip – Trametes cervina

References

  1. ↑ Doyle WA, Blodig W, Veitch NC, Piontek K, Smith AT. Two substrate interaction sites in lignin peroxidase revealed by site-directed mutagenesis. Biochemistry. 1998 Oct 27;37(43):15097-105. PMID:9790672 doi:http://dx.doi.org/10.1021/bi981633h
  2. ↑ Zhong SM, Sun N, Liu HX, Niu YQ, Wu Y. Reduction of facial pigmentation of melasma by topical lignin peroxidase: A novel fast-acting skin-lightening agent. Exp Ther Med. 2015 Feb;9(2):341-344. Epub 2014 Dec 8. PMID:25574195 doi:http://dx.doi.org/10.3892/etm.2014.2118

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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