Gelsolin

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</StructureSection>
</StructureSection>
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== 3D Structures of gelsolin ==
 
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 
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{{#tree:id=OrganizedByTopic|openlevels=0|
 
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* GLS residues 1-782
 
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**[[3ffn]] – hGLS – human <br />
 
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**[[6jeg]], [[6jeh]], [[6jco]] - hGLS (mutant) <br />
 
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**[[2fgh]] – hoGLS+ATP – horse <br />
 
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**[[1d0n]] - hoGLS <br />
 
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**[[2x1o]], [[2x1p]], [[2x1q]] – GLS nanobody - Llama
 
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* GLS domain S1 residues 51-178
 
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**[[5zz0]] – hGLS <br />
 
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**[[5h3m]], [[5h3n]] – hGLS – NMR<br />
 
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**[[2ff3]] - hGLS +N-WASP+actin<br />
 
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**[[2ff6]] - hGLS +Ciboulot domain 2+actin<br />
 
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**[1mdu]] - hGLS +chActin – chicken<br />
 
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**[[1d4x]] - hGLS +CeActin+Mg-ATP – ''Caenorhabditis elegans''<br />
 
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**[[1esv]] - hGLS +rActin+latrunculin – rabbit<br />
 
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**[[1eqy]], [[1p8z]], [[5ubo]] - hGLS +rActin<br />
 
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**[[1yvn]] - hGLS +yActin (mutant) – yeast<br />
 
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**[[1yag]] - hGLS +yActin<br />
 
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**[[1t44]] - hGLS/thymosin β-4 C-terminal fusion+rActin<br />
 
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**[[1kcq]], [[5dd2]] – hGLS +ion<br />
 
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**[[1c0f]], [[1mdu]], [[1nmd]] - hGLS + Actin+Ca-ATP <br />
 
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**[[1c0g]], [[1dej]] - hGLS +Actin (mutant)<br />
 
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**[[3a5l]], [[3a5m]], [[3a5n]], [[3a5o]] - hGLS (mutant)+Actin (mutant)<br />
 
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**[[3ci5]], [[3cip]], [[1nlv]] – DdGLS +actin - ''Dictyostelium discoideum''<br />
 
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**[[1nm1]] - DdGLS +actin+Mg-ATP<br />
 
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**[[3cjb]] - rGLS +rActin<br />
 
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**[[3cjc]] - rGLS +rActin+DNAse I<br />
 
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**[[4cbu]], [[4cbw]], [[4cbx]], [[5mvv]], [[6i4d]], [[6i4e]], [[6i4f]], [[6i4g]], [[6i4h]], [[6i4i]], [[6i4j]], [[6i4k]], [[6i4l]], [[6i4m]] - mGLS +actin+ nucleotide<br />
 
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*GLS S2 residues 178-293
 
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**[[5fae]], [[5faf]], [[5o2z]] - hGLS (mutant) <br />
 
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**[[4s10]], [[6h1f]] - hGLS (mutant) + antibody<br />
 
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* GLS domains S1-S3 residues 52-426
 
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**[[3ffk]] – hGLS +actin <br />
 
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**[[1rgi]] - hoGLS +actin <br />
 
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* GLS domains S4-S6 residues 439-782
 
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**[[1h1v]] - hGLS +actin + Ca + ATP<br />
 
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**[[2fh1]], [[2fh2]], [[2fh3]], [[2fh4]], [[1p8x]] – hGLS + Ca<br />
 
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**[[1nph]] - mGLS +Ca – mouse<br />
 
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}}
 
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 09:09, 9 July 2019

Human gelsolin S4-S6 (gold) complex with actin (cyan), ATP and Ca+2 ion (green) (PDB entry 1h1v)

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References

  1. Sun HQ, Yamamoto M, Mejillano M, Yin HL. Gelsolin, a multifunctional actin regulatory protein. J Biol Chem. 1999 Nov 19;274(47):33179-82. PMID:10559185
  2. Choe H, Burtnick LD, Mejillano M, Yin HL, Robinson RC, Choe S. The calcium activation of gelsolin: insights from the 3A structure of the G4-G6/actin complex. J Mol Biol. 2002 Dec 6;324(4):691-702. PMID:12460571

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Michal Harel, Alexander Berchansky, Jaime Prilusky

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