Mandelate dehydrogenase

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== Structural highlights ==
== Structural highlights ==
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The biological assembly of SMD from ''Pseudomonas putida'' is <scene name='51/516477/Cv/3'>homotetramer</scene>. The <scene name='51/516477/Cv/5'>poor substrate indolelactate binds in the active site</scene> of SMD<ref>PMID:19465768</ref>. Water molecules shown as red spheres.
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The biological assembly of SMD from ''Pseudomonas putida'' is <scene name='51/516477/Cv/7'>homotetramer</scene>. The <scene name='51/516477/Cv/8'>poor substrate indolelactate binds in the active site</scene> of SMD<ref>PMID:19465768</ref>. Water molecules shown as red spheres.
</StructureSection>
</StructureSection>
==3D structures of mandelate dehydrogenase==
==3D structures of mandelate dehydrogenase==

Revision as of 10:09, 9 July 2019

Structure of S-mandelate dehydrogenase tetramer complex with 3-indolelactate and flavin mononucleotide (PDB entry 2a7p)

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3D structures of mandelate dehydrogenase

Updated on 09-July-2019

References

  1. Lehoux IE, Mitra B. (S)-Mandelate dehydrogenase from Pseudomonas putida: mechanistic studies with alternate substrates and pH and kinetic isotope effects. Biochemistry. 1999 May 4;38(18):5836-48. PMID:10231535 doi:http://dx.doi.org/10.1021/bi990024m
  2. Sukumar N, Dewanti A, Merli A, Rossi GL, Mitra B, Mathews FS. Structures of the G81A mutant form of the active chimera of (S)-mandelate dehydrogenase and its complex with two of its substrates. Acta Crystallogr D Biol Crystallogr. 2009 Jun;65(Pt 6):543-52. Epub 2009, May 15. PMID:19465768 doi:10.1107/S0907444909010270

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Michal Harel, Alexander Berchansky

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