6n0j
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The complex of CCG-222740 bound to pirin== |
| - | + | <StructureSection load='6n0j' size='340' side='right'caption='[[6n0j]], [[Resolution|resolution]] 1.79Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6n0j]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N0J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6N0J FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=K8S:(3S)-N-(4-chlorophenyl)-5,5-difluoro-1-[3-(furan-2-yl)benzene-1-carbonyl]piperidine-3-carboxamide'>K8S</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Quercetin_2,3-dioxygenase Quercetin 2,3-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.24 1.13.11.24] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6n0j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n0j OCA], [http://pdbe.org/6n0j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6n0j RCSB], [http://www.ebi.ac.uk/pdbsum/6n0j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6n0j ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PIR_HUMAN PIR_HUMAN]] Possible transcriptional coregulator. May contribute to the regulation of cellular processes via its interaction with BCL3. May be required for efficient terminal myeloid maturation of hematopoietic cells. May play a role in the regulation of cell migration. May promote apoptosis when overexpressed. Has quercetin 2,3-dioxygenase activity (in vitro).<ref>PMID:9079676</ref> <ref>PMID:17288615</ref> <ref>PMID:20010624</ref> <ref>PMID:20711196</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Quercetin 2,3-dioxygenase]] | ||
| + | [[Category: Jin, X]] | ||
| + | [[Category: Lisabeth, E M]] | ||
| + | [[Category: Neubig, R]] | ||
| + | [[Category: Beta barrel]] | ||
| + | [[Category: Co-transcription factor]] | ||
| + | [[Category: Iron-binding]] | ||
| + | [[Category: Oxidoreductase]] | ||
Revision as of 05:46, 10 July 2019
The complex of CCG-222740 bound to pirin
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