6qf5

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'''Unreleased structure'''
 
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The entry 6qf5 is ON HOLD until Paper Publication
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==X-Ray structure of human Aquaporin 2 crystallized on a silicon chip==
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<StructureSection load='6qf5' size='340' side='right'caption='[[6qf5]], [[Resolution|resolution]] 3.70&Aring;' scene=''>
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Authors: Lieske, J., Cerv, M., Kreida, S., Barthelmess, M., Fischer, P., Pakendorf, T., Yefanov, O., Mariani, V., Seine, T., Ross, B.H., Crosas, E., Lorbeer, O., Burkhardt, A., Lane, T.J., Guenther, S., Bergtholdt, J., Schoen, S., Tornroth-Horsefield, S., Chapman, H.N., Meents, A.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6qf5]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QF5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QF5 FirstGlance]. <br>
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Description: X-Ray structure of human Aquaporin 2 crystallized on a silicon chip
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6qf1|6qf1]], [[6qf2|6qf2]], [[6qf3|6qf3]], [[6qf4|6qf4]]</td></tr>
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[[Category: Schoen, S]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qf5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qf5 OCA], [http://pdbe.org/6qf5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qf5 RCSB], [http://www.ebi.ac.uk/pdbsum/6qf5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qf5 ProSAT]</span></td></tr>
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</table>
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== Disease ==
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[[http://www.uniprot.org/uniprot/AQP2_HUMAN AQP2_HUMAN]] Nephrogenic diabetes insipidus. The disease is caused by mutations affecting the gene represented in this entry.
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== Function ==
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[[http://www.uniprot.org/uniprot/AQP2_HUMAN AQP2_HUMAN]] Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Barthelmess, M]]
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[[Category: Bergtholdt, J]]
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[[Category: Burkhardt, A]]
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[[Category: Cerv, M]]
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[[Category: Chapman, H N]]
[[Category: Crosas, E]]
[[Category: Crosas, E]]
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[[Category: Fischer, P]]
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[[Category: Guenther, S]]
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[[Category: Kreida, S]]
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[[Category: Lane, T J]]
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[[Category: Lieske, J]]
[[Category: Lorbeer, O]]
[[Category: Lorbeer, O]]
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[[Category: Kreida, S]]
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[[Category: Mariani, V]]
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[[Category: Meents, A]]
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[[Category: Pakendorf, T]]
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[[Category: Ross, B H]]
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[[Category: Schoen, S]]
[[Category: Seine, T]]
[[Category: Seine, T]]
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[[Category: Chapman, H.N]]
 
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[[Category: Burkhardt, A]]
 
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[[Category: Cerv, M]]
 
[[Category: Tornroth-Horsefield, S]]
[[Category: Tornroth-Horsefield, S]]
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[[Category: Pakendorf, T]]
 
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[[Category: Ross, B.H]]
 
[[Category: Yefanov, O]]
[[Category: Yefanov, O]]
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[[Category: Bergtholdt, J]]
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[[Category: Human aquaporin 2]]
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[[Category: Lieske, J]]
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[[Category: Membrane protein]]
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[[Category: Lane, T.J]]
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[[Category: On-chip crystallization]]
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[[Category: Fischer, P]]
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[[Category: Serial crystallography]]
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[[Category: Meents, A]]
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[[Category: Xfel]]
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[[Category: Mariani, V]]
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[[Category: Barthelmess, M]]
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[[Category: Guenther, S]]
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Revision as of 05:54, 10 July 2019

X-Ray structure of human Aquaporin 2 crystallized on a silicon chip

PDB ID 6qf5

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