Glucose-1-phosphate thymidylyltransferase
From Proteopedia
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</StructureSection> | </StructureSection> | ||
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| - | ==3D structures of glucose-1-phosphate thymidylyltransferase== | ||
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| - | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| - | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
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| - | *RmlA | ||
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| - | **[[1fzw]] – PaRmlA – ''Pseudomonas aeruginosa''<br /> | ||
| - | **[[4ho0]] – AtRmlA – ''Aneurinibacillus thermoaerophilus''<br /> | ||
| - | **[[5ids]] – BvRmlA – ''Burkholderia vietnamiensis''<br /> | ||
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| - | *RmlA binary complexes | ||
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| - | **[[1fxo]] – PaRmlA + TMP <br /> | ||
| - | **[[1g2v]] – PaRmlA + TTP <br /> | ||
| - | **[[4ho3]] – AtRmlA + TTP <br /> | ||
| - | **[[1iim]] – SeRmlA + TTP – ''Salmonella enterica''<br /> | ||
| - | **[[1mp3]] – SeRmlA (mutant) + TTP <br /> | ||
| - | **[[3pkp]] – SeRmlA (mutant) + deoxy-ATP <br /> | ||
| - | **[[3pkq]] – SeRmlA + deoxy-GTP <br /> | ||
| - | **[[1lvw]] – RmlA + TDP – ''methanothermobacter thermautotrophicus'' <br /> | ||
| - | **[[1g23]] – PaRmlA + DGP <br /> | ||
| - | **[[4ho2]] – AtRmlA + thymidine <br /> | ||
| - | **[[4ho5]] – AtRmlA + deoxythymidine-diphospho-α-D-glucose <br /> | ||
| - | **[[1g1l]] – PaRmlA + deoxythymidine-diphospho-α-D-glucose <br /> | ||
| - | **[[1g3l]] – PaRmlA + deoxythymidine-β-L-rhamnose <br /> | ||
| - | **[[4arw]], [[4asj]], [[4asy]], [[4b2x]], [[4b3u]], [[4b42]], [[4b4b]], [[4b4g]], [[4b4m]], [[4b5b]], [[3zlk]], [[3zll]], [[4b2w]], [[5fts]], [[5ftv]], [[5fu0]], [[5fu8]], [[5fuh]], [[5fye]] – PaRmlA + inhibitor <br /> | ||
| - | **[[1iin]] – SeRmlA + UDP-glucose <br /> | ||
| - | **[[1mp4]], [[1mp5]] – SeRmlA (mutant) + UDP-glucose <br /> | ||
| - | **[[4hoc]] – AtRmlA + UDP-NAG <br /> | ||
| - | **[[1h5s]] – EcRmlA + TMP – ''Escherichia coli''<br /> | ||
| - | **[[1h5t]] – EcRmlA + TDP-glucose <br /> | ||
| - | **[[1mc3]] – EcRmlA + TTP <br /> | ||
| - | **[[5idt]] – BvRmlA + thymidine <br /> | ||
| - | **[[6n0u]] – RmlA + deoxythymidine-β-L-rhamnose – ''Burkholdria phymatum''<br /> | ||
| - | **[[6b5e]] – MtRmlA + TDP-glucose – ''Mycobacterium tuberculosis''<br /> | ||
| - | **[[6b5k]] – MtRmlA + TTP <br /> | ||
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| - | *RmlA ternary complexes | ||
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| - | **[[1g0r]] – PaRmlA + DGP + thymidine <br /> | ||
| - | **[[4ho4]] – AtRmlA + DGP + thymidine <br /> | ||
| - | **[[4ho6]] – AtRmlA + UDP-glucose + UTP<br /> | ||
| - | **[[4ho9]] – AtRmlA + UDP-galactose + UTP<br /> | ||
| - | **[[4ho8]] – AtRmlA + UDP-glucose + thymidine<br /> | ||
| - | **[[1h5r]] – EcRmlA + DGP + thymidine <br /> | ||
| - | **[[4ecm]] – RmlA + TDP-glucose + pyrophosphate – ''Bacillus anthracis''<br /> | ||
| - | **[[5ify]] – BvRmlA + deoxy-UMP + deoxy-thymidine-rhamnose <br /> | ||
| - | **[[6b5e]] – RmlA + deoxythymidine-diphospho-α-D-glucose + thymidine-5-phosphate – ''Mycobacterium tuberculosis''<br /> | ||
| - | **[[6b5e]] – RmlA + thymidine-5’-triphosphate + thymidine-5’-diphosphate <br /> | ||
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== References == | == References == | ||
Current revision
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References
- ↑ PAZUR JH, SHUEY EW. The enzymatic synthesis of thymidine diphosphate glucose and its conversion to thymidine diphosphate rhamnose. J Biol Chem. 1961 Jun;236:1780-5. PMID:13733719
- ↑ Blankenfeldt W, Asuncion M, Lam JS, Naismith JH. The structural basis of the catalytic mechanism and regulation of glucose-1-phosphate thymidylyltransferase (RmlA). EMBO J. 2000 Dec 15;19(24):6652-63. PMID:11118200 doi:http://dx.doi.org/10.1093/emboj/19.24.6652
