Glycosyltransferase
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
The <scene name='46/467293/Cv/5'>active site</scene> of cyclodextrin GT contains <scene name='46/467293/Cv/6'>three catalytic residues</scene><ref>PMID:7493956</ref>. Water molecules are shown as red spheres. | The <scene name='46/467293/Cv/5'>active site</scene> of cyclodextrin GT contains <scene name='46/467293/Cv/6'>three catalytic residues</scene><ref>PMID:7493956</ref>. Water molecules are shown as red spheres. | ||
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| + | ==3D structures of glycosyltransferase== | ||
| + | [[Glycosyltransferase 3D structures]] | ||
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</StructureSection> | </StructureSection> | ||
==3D structures of glycosyltransferase== | ==3D structures of glycosyltransferase== | ||
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*β-1,4-galactosyltransferase 1 (BGT) | *β-1,4-galactosyltransferase 1 (BGT) | ||
| + | **[[6fwu]], [[6fwt]] - hBGT 1 catalytic domain<br /> | ||
**[[2fy7]] - hBGT 1 catalytic domain (mutant) <br /> | **[[2fy7]] - hBGT 1 catalytic domain (mutant) <br /> | ||
**[[1fgx]] - bBGT 1 catalytic domain – bovine<br /> | **[[1fgx]] - bBGT 1 catalytic domain – bovine<br /> | ||
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**[[2rit]], [[4kxo]] – hGTB<br /> | **[[2rit]], [[4kxo]] – hGTB<br /> | ||
| - | **[[2pgv]], [[2pgy]], [[2riz]], [[2rj5]], [[1wsz]], [[2o1f]], [[2o1g]], [[5cql]], [[5cqm]], [[5cqn]], [[5cqo]], [[5cqp]], [[5cmf]], [[5cmg]], [[5cmh]], [[5cmi]], [[5cmj]], [[3ioh]] – hGTB (mutant) <br /> | + | **[[2pgv]], [[2pgy]], [[2riz]], [[2rj5]], [[1wsz]], [[2o1f]], [[2o1g]], [[5cql]], [[5cqm]], [[5cqn]], [[5cqo]], [[5cqp]], [[5cmf]], [[5cmg]], [[5cmh]], [[5cmi]], [[5cmj]], [[3ioh]], [[6bjm]], [[6bjl]], [[6bjk]], [[6bjj]], [[6bji]], [[6gwz]], [[6gwy]], [[6gx2]], [[6gx1]], [[6gx0]] – hGTB (mutant) <br /> |
**[[2rix]] – hGTB + UDP<br /> | **[[2rix]] – hGTB + UDP<br /> | ||
**[[3ioj]], [[2olh]], [[5m7b]], [[5m7c]], [[5m7d]] – hGTB (mutant) + UDP<br /> | **[[3ioj]], [[2olh]], [[5m7b]], [[5m7c]], [[5m7d]] – hGTB (mutant) + UDP<br /> | ||
Revision as of 07:32, 16 July 2019
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3D structures of glycosyltransferase
Updated on 16-July-2019
References
- ↑ Williams GJ, Thorson JS. Natural product glycosyltransferases: properties and applications. Adv Enzymol Relat Areas Mol Biol. 2009;76:55-119. PMID:18990828
- ↑ Qasba PK, Ramakrishnan B, Boeggeman E. Structure and function of beta -1,4-galactosyltransferase. Curr Drug Targets. 2008 Apr;9(4):292-309. PMID:18393823
- ↑ Jadhav SK, Patel KA, Dholakia BB, Khan BM. Structural characterization of a flavonoid glycosyltransferase from Withania somnifera. Bioinformation. 2012;8(19):943-9. doi: 10.6026/97320630008943. Epub 2012 Oct 1. PMID:23144555 doi:http://dx.doi.org/10.6026/97320630008943
- ↑ Yoshida A, Kobayashi K, Manya H, Taniguchi K, Kano H, Mizuno M, Inazu T, Mitsuhashi H, Takahashi S, Takeuchi M, Herrmann R, Straub V, Talim B, Voit T, Topaloglu H, Toda T, Endo T. Muscular dystrophy and neuronal migration disorder caused by mutations in a glycosyltransferase, POMGnT1. Dev Cell. 2001 Nov;1(5):717-24. PMID:11709191
- ↑ Knegtel RM, Strokopytov B, Penninga D, Faber OG, Rozeboom HJ, Kalk KH, Dijkhuizen L, Dijkstra BW. Crystallographic studies of the interaction of cyclodextrin glycosyltransferase from Bacillus circulans strain 251 with natural substrates and products. J Biol Chem. 1995 Dec 8;270(49):29256-64. PMID:7493956
