This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6nvb
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of kallikrein-4== | |
| - | + | <StructureSection load='6nvb' size='340' side='right'caption='[[6nvb]], [[Resolution|resolution]] 1.64Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6nvb]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NVB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NVB FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6nvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nvb OCA], [http://pdbe.org/6nvb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nvb RCSB], [http://www.ebi.ac.uk/pdbsum/6nvb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nvb ProSAT]</span></td></tr> |
| - | [[Category: Buckle, A | + | </table> |
| - | [[Category: Riley, B | + | == Disease == |
| - | [[Category: | + | [[http://www.uniprot.org/uniprot/KLK4_HUMAN KLK4_HUMAN]] Defects in KLK4 are the cause of amelogenesis imperfecta hypomaturation type 2A1 (AI2A1) [MIM:[http://omim.org/entry/204700 204700]]. AI2A1 is an autosomal recessive defect of enamel formation. The disorder involves both primary and secondary dentitions. The teeth have a shiny agar jelly appearance and the enamel is softer than normal. Brown pigment is present in middle layers of enamel.<ref>PMID:15235027</ref> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/KLK4_HUMAN KLK4_HUMAN]] Involved in enamel formation.<ref>PMID:15235027</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Buckle, A M]] | ||
| + | [[Category: McGowan, S]] | ||
| + | [[Category: Riley, B T]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Klk4]] | ||
| + | [[Category: Protease]] | ||
Revision as of 10:47, 17 July 2019
Crystal structure of kallikrein-4
| |||||||||||
Categories: Large Structures | Buckle, A M | McGowan, S | Riley, B T | Hydrolase | Klk4 | Protease
