3rg2
From Proteopedia
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==Structure of a two-domain NRPS fusion protein containing the EntE adenylation domain and EntB aryl-carrier protein from enterobactin biosynthesis== | ==Structure of a two-domain NRPS fusion protein containing the EntE adenylation domain and EntB aryl-carrier protein from enterobactin biosynthesis== | ||
| - | <StructureSection load='3rg2' size='340' side='right' caption='[[3rg2]], [[Resolution|resolution]] 3.10Å' scene=''> | + | <StructureSection load='3rg2' size='340' side='right'caption='[[3rg2]], [[Resolution|resolution]] 3.10Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3rg2]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RG2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RG2 FirstGlance]. <br> | <table><tr><td colspan='2'>[[3rg2]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RG2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RG2 FirstGlance]. <br> | ||
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rg2 OCA], [http://pdbe.org/3rg2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3rg2 RCSB], [http://www.ebi.ac.uk/pdbsum/3rg2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3rg2 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rg2 OCA], [http://pdbe.org/3rg2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3rg2 RCSB], [http://www.ebi.ac.uk/pdbsum/3rg2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3rg2 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | {{Large structure}} | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/ENTE_ECOLI ENTE_ECOLI]] Activates the carboxylate group of 2,3-dihydroxy-benzoate (2,3-DHB), via ATP-dependent PPi exchange reactions, to the acyladenylate. Then, catalyzes the acylation of holo-EntB with 2,3-DHB adenylate, preparing that molecule for amide bond formation with L-serine. | [[http://www.uniprot.org/uniprot/ENTE_ECOLI ENTE_ECOLI]] Activates the carboxylate group of 2,3-dihydroxy-benzoate (2,3-DHB), via ATP-dependent PPi exchange reactions, to the acyladenylate. Then, catalyzes the acylation of holo-EntB with 2,3-DHB adenylate, preparing that molecule for amide bond formation with L-serine. | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Ecoli]] | [[Category: Ecoli]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Gulick, A M]] | [[Category: Gulick, A M]] | ||
[[Category: Sundlov, J A]] | [[Category: Sundlov, J A]] | ||
Revision as of 11:36, 17 July 2019
Structure of a two-domain NRPS fusion protein containing the EntE adenylation domain and EntB aryl-carrier protein from enterobactin biosynthesis
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