5bne
From Proteopedia
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==Bianthranilate-like inhibitor with 6 atom "line" and phosphonate "hook" fishing for hydrogen bond donors in Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)== | ==Bianthranilate-like inhibitor with 6 atom "line" and phosphonate "hook" fishing for hydrogen bond donors in Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)== | ||
| - | <StructureSection load='5bne' size='340' side='right' caption='[[5bne]], [[Resolution|resolution]] 2.15Å' scene=''> | + | <StructureSection load='5bne' size='340' side='right'caption='[[5bne]], [[Resolution|resolution]] 2.15Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5bne]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BNE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BNE FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5bne]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BNE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BNE FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7P3:2-[(2-CARBOXYPHENYL)AMINO]-5-[(5-PHOSPHONOPENTYL)OXY]BENZOIC+ACID'>7P3</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7P3:2-[(2-CARBOXYPHENYL)AMINO]-5-[(5-PHOSPHONOPENTYL)OXY]BENZOIC+ACID'>7P3</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3qr9|3qr9]], [[4ij1|4ij1]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3qr9|3qr9]], [[4ij1|4ij1]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trpD, Rv2192c, MTCY190.03c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Anthranilate_phosphoribosyltransferase Anthranilate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.18 2.4.2.18] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Anthranilate_phosphoribosyltransferase Anthranilate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.18 2.4.2.18] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bne FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bne OCA], [http://pdbe.org/5bne PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bne RCSB], [http://www.ebi.ac.uk/pdbsum/5bne PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bne FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bne OCA], [http://pdbe.org/5bne PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bne RCSB], [http://www.ebi.ac.uk/pdbsum/5bne PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5bne ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Phosphoribosyltransferase|Phosphoribosyltransferase]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Anthranilate phosphoribosyltransferase]] | [[Category: Anthranilate phosphoribosyltransferase]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Myctu]] | ||
[[Category: Baker, E N]] | [[Category: Baker, E N]] | ||
[[Category: Evans, G L]] | [[Category: Evans, G L]] | ||
Revision as of 12:22, 17 July 2019
Bianthranilate-like inhibitor with 6 atom "line" and phosphonate "hook" fishing for hydrogen bond donors in Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
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Categories: Anthranilate phosphoribosyltransferase | Large Structures | Myctu | Baker, E N | Evans, G L | Lott, J S | Structural genomic | Anprt | Complex | Inhibitor | Lobenzarit-like analogue | Magnesium binding | Phosphoribosylpyrophosphate | Phosphoribosyltransferase | Prpp | Tbsgc | Transferase-transferase inhibitor complex | Trpd
