6d28
From Proteopedia
(Difference between revisions)
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==Crystal Structure of the N-domain of the ER Hsp90 chaperone GRP94 in complex with the specific ligand NECA== | ==Crystal Structure of the N-domain of the ER Hsp90 chaperone GRP94 in complex with the specific ligand NECA== | ||
- | <StructureSection load='6d28' size='340' side='right' caption='[[6d28]], [[Resolution|resolution]] 1.75Å' scene=''> | + | <StructureSection load='6d28' size='340' side='right'caption='[[6d28]], [[Resolution|resolution]] 1.75Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[6d28]] is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1qy5 1qy5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6D28 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6D28 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6d28]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Canlf Canlf]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1qy5 1qy5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6D28 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6D28 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=M2M:1-METHOXY-2-(2-METHOXYETHOXY)ETHANE'>M2M</scene>, <scene name='pdbligand=NEC:N-ETHYL-5-CARBOXAMIDO+ADENOSINE'>NEC</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=M2M:1-METHOXY-2-(2-METHOXYETHOXY)ETHANE'>M2M</scene>, <scene name='pdbligand=NEC:N-ETHYL-5-CARBOXAMIDO+ADENOSINE'>NEC</scene></td></tr> | ||
+ | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HSP90B1, GRP94, TRA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9615 CANLF])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6d28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6d28 OCA], [http://pdbe.org/6d28 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6d28 RCSB], [http://www.ebi.ac.uk/pdbsum/6d28 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6d28 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6d28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6d28 OCA], [http://pdbe.org/6d28 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6d28 RCSB], [http://www.ebi.ac.uk/pdbsum/6d28 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6d28 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
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</div> | </div> | ||
<div class="pdbe-citations 6d28" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 6d28" style="background-color:#fffaf0;"></div> | ||
+ | |||
+ | ==See Also== | ||
+ | *[[Heat Shock Proteins|Heat Shock Proteins]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
+ | [[Category: Canlf]] | ||
+ | [[Category: Large Structures]] | ||
[[Category: Gewirth, D T]] | [[Category: Gewirth, D T]] | ||
[[Category: Jivan, A]] | [[Category: Jivan, A]] |
Revision as of 12:29, 17 July 2019
Crystal Structure of the N-domain of the ER Hsp90 chaperone GRP94 in complex with the specific ligand NECA
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Categories: Canlf | Large Structures | Gewirth, D T | Jivan, A | Nicchitta, C V | Soldano, K L | Chaperone | Grp94 | Hsp90 | Inhibitor | Neca