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1ytf

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[[Image:1ytf.jpg|left|200px]]
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{{Structure
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|LIGAND= <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ytf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ytf OCA], [http://www.ebi.ac.uk/pdbsum/1ytf PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ytf RCSB]</span>
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'''YEAST TFIIA/TBP/DNA COMPLEX'''
'''YEAST TFIIA/TBP/DNA COMPLEX'''
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[[Category: Sargent, D F.]]
[[Category: Sargent, D F.]]
[[Category: Tan, S.]]
[[Category: Tan, S.]]
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[[Category: complex]]
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[[Category: Complex]]
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[[Category: dna]]
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[[Category: Dna]]
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[[Category: transcription regulation]]
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[[Category: Transcription regulation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 24 09:40:28 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:21:32 2008''
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Revision as of 06:40, 24 April 2008

Image:1ytf.jpg

Template:STRUCTURE 1ytf

YEAST TFIIA/TBP/DNA COMPLEX


Overview

The X-ray crystal structure of the transcription factor IIA (TFIIA) in complex with the TATA-box-binding protein (TBP) and TATA-element DNA is presented at 2.5 A resolution. TFIIA is composed of a beta-barrel and a four-helix bundle motif that together have a boot-like appearance. The beta-barrel extends the TBP beta-sheet and bridges over the DNA major groove immediately upstream of the TATA box. The four-helix bundle contributes substantially to the surface of the complex available for interaction with additional transcription factors.

About this Structure

1YTF is a Protein complex structure of sequences from Saccharomyces cerevisiae. The following page contains interesting information on the relation of 1YTF with [TATA-Binding Protein]. Full crystallographic information is available from OCA.

Reference

Crystal structure of a yeast TFIIA/TBP/DNA complex., Tan S, Hunziker Y, Sargent DF, Richmond TJ, Nature. 1996 May 9;381(6578):127-51. PMID:8610010 Page seeded by OCA on Thu Apr 24 09:40:28 2008

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