NAD synthase

(Difference between revisions)

Revision as of 12:15, 21 July 2019

NAD+ synthase complex with Mg+2 (green), ATP and deamino-NAD (PDB entry 1xng)

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Updated on 21-July-2019

↑ Suda Y, Tachikawa H, Yokota A, Nakanishi H, Yamashita N, Miura Y, Takahashi N. Saccharomyces cerevisiae QNS1 codes for NAD(+) synthetase that is functionally conserved in mammals. Yeast. 2003 Aug;20(11):995-1005. PMID:12898714 doi:http://dx.doi.org/10.1002/yea.1008
↑ Kang GB, Kim YS, Im YJ, Rho SH, Lee JH, Eom SH. Crystal structure of NH3-dependent NAD+ synthetase from Helicobacter pylori. Proteins. 2005 Mar 1;58(4):985-8. PMID:15645437 doi:10.1002/prot.20377

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 == Structural highlights ==
-The <scene name='54/541072/Cv/4'>ATP binding site</scene> contains <scene name='54/541072/Cv/5'>Mg+2 ion</scene>.  The <scene name='54/541072/Cv/7'>NAD binding site is located in the interface of the 2 subunits</scene><ref>PMID:15645437</ref>. Water molecules shown as red spheres.
+The <scene name='54/541072/Cv/8'>ATP binding site</scene> contains <scene name='54/541072/Cv/9'>Mg+2 ion</scene>. The <scene name='54/541072/Cv/10'>NAD binding site is located in the interface of the 2 subunits</scene><ref>PMID:15645437</ref>. Water molecules are shown as red spheres.
 </StructureSection>
 == 3D Structures of NAD+ synthase ==