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Neuroglobin

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== Structural highlights ==
== Structural highlights ==
-
*<scene name='44/443478/Cv/14'>Heme binding site</scene>.
+
*<scene name='44/443478/Cv/15'>Heme binding site</scene>. Water molecules are shown as red spheres.
-
*<scene name='44/443478/Cv/9'>1st Xe coordination site</scene>.
+
*<scene name='44/443478/Cv/16'>1st Xe coordination site</scene>.
-
*<scene name='44/443478/Cv/10'>2nd Xe coordination site</scene>.
+
*<scene name='44/443478/Cv/17'>2nd Xe coordination site</scene>.
-
*<scene name='44/443478/Cv/11'>3rd Xe binding site</scene>.
+
*<scene name='44/443478/Cv/18'>3rd Xe binding site</scene>.
-
*<scene name='44/443478/Cv/12'>4th Xe binding site</scene>.
+
*<scene name='44/443478/Cv/19'>4th Xe binding site</scene>.
</StructureSection>
</StructureSection>
== 3D Structures of Neuroglobin ==
== 3D Structures of Neuroglobin ==

Revision as of 13:33, 23 July 2019

Mouse neuroglobin showing the heme and complexed with sulfate and Xe 3gk9

Drag the structure with the mouse to rotate

3D Structures of Neuroglobin

Updated on 23-July-2019

5eet – mNGB – mouse
3gk9, 3gkt, 2vry, 1q1f, 4mu5, 4nzi, 4o1t, 4o4t, 5eoh, 5eqm, 5eu2, 5ev5, 5eyj, 5eys, 5f0b, 5f2a, 5nvi, 5nw6, 5o17, 5o18, 5o1k, 5o27, 6eye – mNGB (mutant)
3gln, 1w92, 4o2g, 4o35 – mNGB (mutant) + CO
4o4z – mNGB (mutant) + N2O
5mjc, 5mjd – mNGB + O2
1oj6 – hNGB (mutant) - human
4mpm – hNGB
4b4y – NGB – Symsagittifera roscoffensis

References

  1. ↑ Uzan J, Dewilde S, Burmester T, Hankeln T, Moens L, Hamdane D, Marden MC, Kiger L. Neuroglobin and other hexacoordinated hemoglobins show a weak temperature dependence of oxygen binding. Biophys J. 2004 Aug;87(2):1196-204. PMID:15298922 doi:http://dx.doi.org/10.1529/biophysj.104.042168
  2. ↑ Sun F, Mao X, Xie L, Greenberg DA, Jin K. Neuroglobin protein is upregulated in Alzheimer's disease. J Alzheimers Dis. 2013;36(4):659-63. doi: 10.3233/JAD-130323. PMID:23648513 doi:http://dx.doi.org/10.3233/JAD-130323

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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