6a7x
From Proteopedia
(Difference between revisions)
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- | '''Unreleased structure''' | ||
- | + | ==Rat Xanthine oxidoreductase, D428A variant, NAD bound form== | |
- | + | <StructureSection load='6a7x' size='340' side='right'caption='[[6a7x]], [[Resolution|resolution]] 2.15Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[6a7x]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6A7X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6A7X FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BCT:BICARBONATE+ION'>BCT</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=URC:URIC+ACID'>URC</scene></td></tr> | |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6a7x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6a7x OCA], [http://pdbe.org/6a7x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6a7x RCSB], [http://www.ebi.ac.uk/pdbsum/6a7x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6a7x ProSAT]</span></td></tr> |
+ | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/XDH_RAT XDH_RAT]] Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species.<ref>PMID:17301076</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Kawaguchi, Y]] | ||
+ | [[Category: Okamoto, K]] | ||
+ | [[Category: Oxidoreductase]] |
Revision as of 06:05, 24 July 2019
Rat Xanthine oxidoreductase, D428A variant, NAD bound form
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