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6i00
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM informed directed evolution of Nitrilase 4 leads to a change in quaternary structure.== | |
| - | + | <StructureSection load='6i00' size='340' side='right'caption='[[6i00]], [[Resolution|resolution]] 3.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6i00]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6I00 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6I00 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6i00 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6i00 OCA], [http://pdbe.org/6i00 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6i00 RCSB], [http://www.ebi.ac.uk/pdbsum/6i00 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6i00 ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| - | [[Category: Mulelu, A | + | == Function == |
| - | [[Category: Woodward, J | + | [[http://www.uniprot.org/uniprot/NRL4_ARATH NRL4_ARATH]] Highly specific for beta-cyano-L-alanine (Ala(CN)). Low activity with 3-phenylpropionitrile (PPN) or allylcyanide and no activity with indole-3-acetonitrile. Not associated with auxin production but may be involved in cyanide detoxification.<ref>PMID:11060302</ref> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mulelu, A E]] | ||
| + | [[Category: Woodward, J D]] | ||
| + | [[Category: Beta-cyano-l-alanine hydrolase]] | ||
| + | [[Category: Cyanide detoxification]] | ||
| + | [[Category: Helical filament]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Nitrilase]] | ||
Revision as of 06:09, 24 July 2019
Cryo-EM informed directed evolution of Nitrilase 4 leads to a change in quaternary structure.
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