6pdm

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m (Protected "6pdm" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 6pdm is ON HOLD
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==Crystal structure of Human Protein Arginine Methyltransferase 9 (PRMT9)==
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<StructureSection load='6pdm' size='340' side='right'caption='[[6pdm]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
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Authors: Halabelian, L., Tempel, W., Zeng, H., Li, Y., Seitova, A., Hutchinson, A., Bountra, C., Edwards, A.M., Arrowsmith, C.H., Structural Genomics Consortium (SGC)
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6pdm]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PDM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PDM FirstGlance]. <br>
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Description: Crystal structure of Human Protein Arginine Methyltransferase 9 (PRMT9)
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Type_II_protein_arginine_methyltransferase Type II protein arginine methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.320 2.1.1.320] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6pdm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pdm OCA], [http://pdbe.org/6pdm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6pdm RCSB], [http://www.ebi.ac.uk/pdbsum/6pdm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6pdm ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/ANM9_HUMAN ANM9_HUMAN]] Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA). Specifically mediates the symmetrical dimethylation of SF3B2. Involved in the regulation of alternative splicing of pre-mRNA (PubMed:25737013, PubMed:25979344).<ref>PMID:25737013</ref> <ref>PMID:25979344</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Type II protein arginine methyltransferase]]
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[[Category: Arrowsmith, C H]]
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[[Category: Bountra, C]]
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[[Category: Edwards, A M]]
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[[Category: Halabelian, L]]
[[Category: Hutchinson, A]]
[[Category: Hutchinson, A]]
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[[Category: Edwards, A.M]]
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[[Category: Li, Y]]
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[[Category: Arrowsmith, C.H]]
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[[Category: Structural genomic]]
[[Category: Seitova, A]]
[[Category: Seitova, A]]
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[[Category: Structural Genomics Consortium (Sgc)]]
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[[Category: Tempel, W]]
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[[Category: Li, Y]]
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[[Category: Halabelian, L]]
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[[Category: Zeng, H]]
[[Category: Zeng, H]]
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[[Category: Bountra, C]]
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[[Category: Sgc]]
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[[Category: Tempel, W]]
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[[Category: Transferase]]

Revision as of 06:29, 31 July 2019

Crystal structure of Human Protein Arginine Methyltransferase 9 (PRMT9)

PDB ID 6pdm

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