This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


6rvx

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "6rvx" [edit=sysop:move=sysop])
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 6rvx is ON HOLD until Paper Publication
+
==Inward-open structure of the ASCT2 (SLC1A5) mutant C467R in presence of TBOA==
-
 
+
<StructureSection load='6rvx' size='340' side='right'caption='[[6rvx]], [[Resolution|resolution]] 3.61&Aring;' scene=''>
-
Authors:
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[6rvx]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RVX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6RVX FirstGlance]. <br>
-
Description:
+
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6rvy|6rvy]]</td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6rvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rvx OCA], [http://pdbe.org/6rvx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rvx RCSB], [http://www.ebi.ac.uk/pdbsum/6rvx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rvx ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[[http://www.uniprot.org/uniprot/AAAT_HUMAN AAAT_HUMAN]] Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids (PubMed:8702519). Through binding of the fusogenic protein syncytin-1/ERVW-1 may mediate trophoblasts syncytialization, the spontaneous fusion of their plasma membranes, an essential process in placental development (PubMed:10708449, PubMed:23492904).<ref>PMID:10708449</ref> <ref>PMID:23492904</ref> <ref>PMID:8702519</ref> (Microbial infection) Acts as a cell surface receptor for Feline endogenous virus RD114.<ref>PMID:10051606</ref> <ref>PMID:10196349</ref> (Microbial infection) Acts as a cell surface receptor for Baboon M7 endogenous virus.<ref>PMID:10196349</ref> (Microbial infection) Acts as a cell surface receptor for type D simian retroviruses.<ref>PMID:10196349</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
 +
[[Category: Garaeva, A A]]
 +
[[Category: Guskov, A]]
 +
[[Category: Paulino, C]]
 +
[[Category: Slotboom, D J]]
 +
[[Category: Membrane protein]]

Revision as of 06:06, 7 August 2019

Inward-open structure of the ASCT2 (SLC1A5) mutant C467R in presence of TBOA

PDB ID 6rvx

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/6rvx"
Personal tools