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6rj0
From Proteopedia
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<StructureSection load='6rj0' size='340' side='right'caption='[[6rj0]], [[Resolution|resolution]] 3.70Å' scene=''> | <StructureSection load='6rj0' size='340' side='right'caption='[[6rj0]], [[Resolution|resolution]] 3.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6rj0]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RJ0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6RJ0 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6rj0]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Betanodavirus_sp. Betanodavirus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RJ0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6RJ0 FirstGlance]. <br> |
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6rj0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rj0 OCA], [http://pdbe.org/6rj0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rj0 RCSB], [http://www.ebi.ac.uk/pdbsum/6rj0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rj0 ProSAT]</span></td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6rj0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rj0 OCA], [http://pdbe.org/6rj0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rj0 RCSB], [http://www.ebi.ac.uk/pdbsum/6rj0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rj0 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Virus-like particles (VLPs) of the fish virus, Atlantic Cod Nervous necrosis virus (ACNNV), were successfully produced by transient expression of the coat protein in Nicotiana benthamiana plants. VLPs could also be produced in transgenic tobacco BY-2 cells. The protein extracted from plants self-assembled into T = 3 particles, that appeared to be morphologically similar to previously analyzed NNV VLPs when analyzed by high resolution cryo-electron microscopy. Administration of the plant-produced VLPs to sea bass (Dicentrarchus labrax) showed that they could protect the fish against subsequent virus challenge, indicating that plant-produced vaccines may have a substantial future role in aquaculture. | ||
| + | |||
| + | Plant-Made Nervous Necrosis Virus-Like Particles Protect Fish Against Disease.,Marsian J, Hurdiss DL, Ranson NA, Ritala A, Paley R, Cano I, Lomonossoff GP Front Plant Sci. 2019 Jul 9;10:880. doi: 10.3389/fpls.2019.00880. eCollection, 2019. PMID:31354759<ref>PMID:31354759</ref> | ||
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| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 6rj0" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Betanodavirus sp]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Hurdiss, D L]] | [[Category: Hurdiss, D L]] | ||
Revision as of 06:27, 7 August 2019
Atlantic Cod Nervous Necrosis Virus-Like Particle produced in Nicotiana benthamiana
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