6se0
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Class 1 : CENP-A nucleosome== | |
| - | + | <StructureSection load='6se0' size='340' side='right'caption='[[6se0]], [[Resolution|resolution]] 3.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6se0]] is a 10 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6SE0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6SE0 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6se0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6se0 OCA], [http://pdbe.org/6se0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6se0 RCSB], [http://www.ebi.ac.uk/pdbsum/6se0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6se0 ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CENPA_HUMAN CENPA_HUMAN]] Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division. The CENPA-H4 heterotetramer can bind DNA by itself (in vitro).<ref>PMID:20739937</ref> <ref>PMID:21478274</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ali-Ahmad, A]] | ||
| + | [[Category: Bilokapic, S]] | ||
[[Category: Halic, M]] | [[Category: Halic, M]] | ||
| - | + | [[Category: Schafer, I B]] | |
| - | + | ||
| - | [[Category: Schafer, I | + | |
[[Category: Sekulic, N]] | [[Category: Sekulic, N]] | ||
| + | [[Category: Cenp-a]] | ||
| + | [[Category: Centromere]] | ||
| + | [[Category: Centromeric chromatin]] | ||
| + | [[Category: Nuclear protein]] | ||
| + | [[Category: Nucleosome]] | ||
Revision as of 16:49, 14 August 2019
Class 1 : CENP-A nucleosome
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