5qsr
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z136583524== | |
| - | + | <StructureSection load='5qsr' size='340' side='right'caption='[[5qsr]], [[Resolution|resolution]] 3.28Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5qsr]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QSR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5QSR FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NU4:2-methyl-N-(pyridin-4-yl)furan-3-carboxamide'>NU4</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qsr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qsr OCA], [http://pdbe.org/5qsr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qsr RCSB], [http://www.ebi.ac.uk/pdbsum/5qsr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qsr ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Disease == |
| + | [[http://www.uniprot.org/uniprot/STAG1_HUMAN STAG1_HUMAN]] STAG1-related intellectual disability-facial dysmorphism-gastroesophageal reflux syndrome. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/STAG1_HUMAN STAG1_HUMAN]] Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Arrowsmith, C H]] | ||
| + | [[Category: Bountra, C]] | ||
| + | [[Category: Delft, F von]] | ||
| + | [[Category: Edwards, A]] | ||
| + | [[Category: Gavard, A E]] | ||
[[Category: Gileadi, O]] | [[Category: Gileadi, O]] | ||
| - | [[Category: Newman, J | + | [[Category: Katis, V L]] |
| - | [[Category: | + | [[Category: Newman, J A]] |
| - | [[Category: | + | [[Category: Pandda]] |
| - | [[Category: | + | [[Category: Sgc - diamond i04-1 fragment screening]] |
| - | [[Category: | + | [[Category: Transcription]] |
| + | [[Category: Xchemexplorer]] | ||
Revision as of 05:47, 21 August 2019
PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z136583524
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