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6ed7
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of 7,8-diaminopelargonic acid synthase bound to inhibitor MAC13772== | |
| - | + | <StructureSection load='6ed7' size='340' side='right'caption='[[6ed7]], [[Resolution|resolution]] 2.43Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6ed7]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ED7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ED7 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=J4J:2-[(2-nitrophenyl)sulfanyl]acetohydrazide'>J4J</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosylmethionine--8-amino-7-oxononanoate_transaminase Adenosylmethionine--8-amino-7-oxononanoate transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.62 2.6.1.62] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ed7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ed7 OCA], [http://pdbe.org/6ed7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ed7 RCSB], [http://www.ebi.ac.uk/pdbsum/6ed7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ed7 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/A0A0A0GYM0_ECOLX A0A0A0GYM0_ECOLX]] Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor.[HAMAP-Rule:MF_00834] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Adenosylmethionine--8-amino-7-oxononanoate transaminase]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Brown, C M]] | ||
| + | [[Category: Brown, E D]] | ||
| + | [[Category: Chan, J]] | ||
| + | [[Category: Junop, M S]] | ||
[[Category: Zlitni, S]] | [[Category: Zlitni, S]] | ||
| - | [[Category: | + | [[Category: Antibiotic]] |
| - | [[Category: | + | [[Category: Inhibitor adduct complex]] |
| - | [[Category: | + | [[Category: Transferase-antibiotic complex]] |
| - | + | ||
Revision as of 05:50, 21 August 2019
Crystal structure of 7,8-diaminopelargonic acid synthase bound to inhibitor MAC13772
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