Hyaluronidase

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</StructureSection>
</StructureSection>
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==3D structures of hyaluronidase==
 
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 
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{{#tree:id=OrganizedByTopic|openlevels=0|
 
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*Hyaluronidase
 
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**[[2pe4]] – HU-1 – human<br />
 
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**[[1fcq]], [[1fcu]] – bHU – bee<br />
 
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**[[1egu]], [[2brw]] – SpHU – ''Streptococcus pneumoniae'' <br />
 
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**[[4d0q]] – SpHU HUA binding domain<br />
 
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**[[1n7n]], [[1n7o]], [[1n7p]] – SpHU (mutant) <br />
 
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**[[1f1s]] – SaHU – ''Streptococcus agalactiae'' <br />
 
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**[[2c3f]], [[2dp5]], [[2yw0]], [[2yx2]], [[2wb3]], [[2wh7]] - SpyHU – ''Streptococcus pyogenes''<br />
 
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**[[2cbi]], [[2w1q]], [[2w1s]] - CpHU – ''Clostridium perfringens''<br />
 
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**[[2jnk]] - CpHU residues 1498-1628]] - NMR<br />
 
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**[[2atm]] - HU – ''Vespula vulgaris''<br />
 
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**[[4ufq]] – HU – ''Streptomyces koganeiensis''<br />
 
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*Hyaluronidase binary complex
 
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**[[1fcv]] - bHU + HUA<br />
 
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**[[2j88]] - bHU + FAB<br />
 
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**[[1c82]] – SpHU + HUA disaccharide <br />
 
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**[[1f9g]] – SpHU + ascorbate <br />
 
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**[[2brv]]– SpHU + malonate<br />
 
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**[[1loh]], [[1lxk]] - SpHU + glucuronic acid<br />
 
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**[[1n7q]], [[1n7r]] - SpHU (mutant) + glucuronic acid<br />
 
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**[[1ojm]], [[1ojp]] - SpHU + condroitin disaccharide <br />
 
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**[[1ojn]], [[1ojo]] - SpHU (mutant) + condroitin disaccharide <br />
 
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**[[1w3y]] - SpHU + palmitoyl-vitamin C <br />
 
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**[[2brp]] – SpHU + inhibitor<br />
 
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**[[1i8q]] - SaHU + HUA disaccharide <br />
 
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**[[1lxm]] - SaHU + glucuronic acid<br />
 
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**[[2cbj]] - CpHU + PugNac<br />
 
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**[[2j1a]] - CpHU + galactose<br />
 
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**[[2j1e]] - CpHU + LacNac<br />
 
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**[[2j7m]], [[2w1u]], [[2wdb]] - CpHU + carbohydrates<br />
 
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**[[2j62]] - CpHU + GlcNac-statin<br />
 
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**[[2yvv]] - SpyHU + lactose<br />
 
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**[[3eka]] - SpyHU + ascorbate <br />
 
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**[[5diy]] – HU + Map3K 7 interacting protein peptide – ''Thermobaculum terrenum''<br />
 
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}}
 
==Reference==
==Reference==
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<br />
<br />
Created with the participation of [[User:Osnat Herzberg|Osnat Herzberg]], [[User:Eran Hodis|Eran Hodis]], [[User:Joel L. Sussman|Joel L. Sussman]], [[User:Jaime Prilusky|Jaime Prilusky]].
Created with the participation of [[User:Osnat Herzberg|Osnat Herzberg]], [[User:Eran Hodis|Eran Hodis]], [[User:Joel L. Sussman|Joel L. Sussman]], [[User:Jaime Prilusky|Jaime Prilusky]].
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[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 10:21, 21 August 2019

Hyaluronidase complex with hyaluronic acid disaccharide and dimethylarsinate, 1c82

Drag the structure with the mouse to rotate

Reference

  1. Chao KL, Muthukumar L, Herzberg O. Structure of human hyaluronidase-1, a hyaluronan hydrolyzing enzyme involved in tumor growth and angiogenesis. Biochemistry. 2007 Jun 12;46(23):6911-20. Epub 2007 May 16. PMID:17503783 doi:10.1021/bi700382g
  2. Ponnuraj K, Jedrzejas MJ. Mechanism of hyaluronan binding and degradation: structure of Streptococcus pneumoniae hyaluronate lyase in complex with hyaluronic acid disaccharide at 1.7 A resolution. J Mol Biol. 2000 Jun 16;299(4):885-95. PMID:10843845 doi:10.1006/jmbi.2000.3817


Created with the participation of Osnat Herzberg, Eran Hodis, Joel L. Sussman, Jaime Prilusky.

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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